APOA5 antibody from Promab.
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Minor apolipoprotein mainly associated with HDL and to a lesser extent with VLDL. APOA5 may also be associated with chylomicrons. Important determinant of plasma triglyceride (TG) levels by both being a potent stimulator of apo-CII lipoprotein lipase (LPL) TG hydrolysis and an inhibitor of the hepatic VLDL-TG production rate (without affecting the VLDL-apoB production rate).
For research use only.
Fully tested in-house by ABMIUM, or supported by an advanced validation report from a partner reviewed by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Evidence status by application and model.
| Species | WB | IHC | IHC-P | IHC-F | IF/ICC | Flow Cytometry | ELISA | IP | ChIP |
|---|---|---|---|---|---|---|---|---|---|
| Human |
This product is manufactured by Promab and sold through ABMIUM without relabelling.
ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.
Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.
APOA5 (apolipoprotein A5) encodes apolipoprotein A-V (ApoA-V), a liver-enriched minor apolipoprotein associated mainly with HDL and also with triglyceride-rich lipoproteins. APOA5 is an important regulator of plasma triglyceride metabolism and is studied in lipoprotein lipase activity, VLDL handling and systemic lipid homeostasis.
Biological function: Apolipoprotein A-V is a minor plasma apolipoprotein that modulates triglyceride-rich lipoprotein metabolism. Reviewed UniProt describes ApoA-V as a potent stimulator of apo-CII-dependent lipoprotein lipase triglyceride hydrolysis and as an inhibitor of hepatic VLDL-triglyceride production, supporting efficient triglyceride clearance and regulation of circulating triglyceride levels.
