ABMIUM target intelligence
apolipoprotein A5
APOA5 (apolipoprotein A5) encodes apolipoprotein A-V (ApoA-V), a liver-enriched minor apolipoprotein associated mainly with HDL and also with triglyceride-rich lipoproteins. APOA5 is an important regulator of plasma triglyceride metabolism and is studied in lipoprotein lipase activity, VLDL handling and systemic lipid homeostasis.
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Research context & evidence
Target information is kept separate from product-level validation so you can review the biology and the reagent evidence independently.
Apolipoprotein A-V is a minor plasma apolipoprotein that modulates triglyceride-rich lipoprotein metabolism. Reviewed UniProt describes ApoA-V as a potent stimulator of apo-CII-dependent lipoprotein lipase triglyceride hydrolysis and as an inhibitor of hepatic VLDL-triglyceride production, supporting efficient triglyceride clearance and regulation of circulating triglyceride levels.
APOA5 is a focused research target for triglyceride homeostasis, lipoprotein lipase regulation, HDL/VLDL biology and hepatic lipid metabolism. Experimental interpretation should distinguish APOA5 abundance from lipoprotein-particle state and should follow product-specific species, sample, assay and application validation.
Names used across publications, databases and supplier catalogues.
