ACSL4 antibody from Promab.
Know who made it. See the evidence. Buy through one marketplace.
catalyses the conversion of long-chain fatty acids to their active form acyl-CoA for both synthesis of cellular lipids, and degradation via beta-oxidation. Preferentially activates arachidonate and eicosapentaenoate as substrates. Preferentially activates 8,9-EET > 14,15-EET > 5,6-EET > 11,12-EET.
For research use only.
Fully tested in-house by ABMIUM, or supported by an advanced validation report from a partner reviewed by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Evidence status by application and model.
| Species | WB | IHC | IHC-P | IHC-F | IF/ICC | Flow Cytometry | ELISA | IP | ChIP |
|---|---|---|---|---|---|---|---|---|---|
| Human | |||||||||
| Mouse | |||||||||
| Rat |
This product is manufactured by Promab and sold through ABMIUM without relabelling.
ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.
Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.
Acyl-CoA synthetase long chain family member 4 (ACSL4), also known as FACL4 and long-chain-fatty-acid--CoA ligase 4, activates long-chain fatty acids to acyl-CoA esters. Human ACSL4 maps to NCBI Gene 2182 and reviewed UniProtKB O60488; this record links the verified target to related ABMIUM catalogue products.
Biological function: ACSL4 catalyses activation of long-chain fatty acids to fatty acyl-CoA esters for cellular lipid synthesis and fatty-acid degradation. NCBI and reviewed UniProt describe a preference for arachidonate; UniProt also identifies ACSL4 as a ferroptosis activator by generating activated polyunsaturated-fatty-acid substrates that can undergo lipid peroxidation.
