Human Carbonic Anhydrase 4, CA4 ELISA Kit
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Reversible hydration of carbon dioxide. May stimulate the sodium/bicarbonate transporter activity of SLC4A4 that acts in pH homeostasis. It is essential for acid overload removal from the retina and retina epithelium, and acid release in the choriocapillaris in the choroid.
Fully tested in-house by ABMIUM, or supported by an advanced validation report from a partner reviewed by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Evidence status by application and model.
| Evidence | Serum | Plasma | Cell culture supernatants | Ascites | Tissue homogenates |
|---|---|---|---|---|---|
| Compatibility |
This product is manufactured by BT LAB and sold through ABMIUM without relabelling.
ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.
Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.
Carbonic anhydrase 4 (CA4; carbonic anhydrase IV/CA-IV) is a GPI-anchored membrane zinc metalloenzyme with an extracellular catalytic domain. It catalyses reversible CO2 hydration and is studied in extracellular pH regulation, bicarbonate transport, renal physiology and retinal acid handling.
Biological function: CA4 catalyses reversible conversion of carbon dioxide and water to bicarbonate and protons at the cell surface, helping couple extracellular carbon chemistry to pH homeostasis. Reviewed UniProt also supports roles in bicarbonate-transporter activity and retinal acid removal.
