Manufactured by:TriBio Science
RUO

TRO 19622 (Olesoxime), Neurotrophic agent

Neuroregenerative and neuroprotective agent acting at components of the mitochondrial permeability transition pore (MPTP). Rescues motor neurons from axotomy-induced cell death and promotes nerve regeneration following sciatic nerve crush in mice. Reduces ROS and NLRP3 inflammasome activation in...

SKU:
ABM148884-1
Manufacturer SKU
TBI3230-25MG | TBI3230-5MG
Product type
Biochemical Inhibitors
TargetNeurotrophic agent
Purity>98%

Manufacturer provenance

Manufactured by:
TriBio Science
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

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Product description

Neuroregenerative and neuroprotective agent acting at components of the mitochondrial permeability transition pore (MPTP). Rescues motor neurons from axotomy-induced cell death and promotes nerve regeneration following sciatic nerve crush in mice. Reduces ROS and NLRP3 inflammasome activation in a mouse model of intracerebral hemorrhage. Inhibits MPTP opening and protects neurons from apoptosis. Induces oligodendrocyte maturation in culture and promotes myelin regeneration in vivo in a rodent model

Key facts & specifications
Also known as
Olesoxime
Molecular weight
399.65
Form / buffer
powder
Activity
Neuroregenerative and neuroprotective agent acting at components of the mitochondrial permeability transition pore (MPTP). Rescues motor neurons from axotomy-induced cell death and promotes nerve regeneration following sciatic nerve crush in mice. Reduces ROS and NLRP3 inflammasome activation in a mouse model of intracerebral hemorrhage. Inhibits MPTP opening and protects neurons from apoptosis. Induces oligodendrocyte maturation in culture and promotes myelin regeneration in vivo in a rodent model.
Molecular formula
C 27 H 45 NO
Solubility
Soluble in DMSO (up to 20 mg/ml) or in Ethanol (up to 25 mg/ml)
Technical note
Stability: ≥ 1 year.
Identifiers & database references
Manufacturer SKU
TBI3230-25MG | TBI3230-5MG
CAS number
22033-87-0
Storage, stability & shipping
Storage conditions
-20°C
Shipped at
4°C
Long-term storage
-20°C
Compliance & documents
Datasheet
Open datasheet
Safety data sheet
Open SDS
Frequently asked questions
Who manufactured this product?

This product is manufactured by TriBio Science and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

TriBio Science
£327.00