Manufactured by:TriBio Science
RUO

TPCK, Serine protease inhibitor

TPCK is an irreversible inhibitor of the serine protease chymotrypsin. It also inhibits certain cysteine proteases (bromelain, ficin, papain). TPCK inhibited (IC50 = 5 µM) the mitogen-induced activation of pp70s6k, a mitogen-regulated serine/threonine kinase involved in the G1 to S phase...

SKU:
ABM148872-1
Manufacturer SKU
TBI2290-500MG
Product type
Biochemical Inhibitors
TargetSerine protease
Purity>98%

Manufacturer provenance

Manufactured by:
TriBio Science
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

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Product description

TPCK is an irreversible inhibitor of the serine protease chymotrypsin. It also inhibits certain cysteine proteases (bromelain, ficin, papain). TPCK inhibited (IC50 = 5 µM) the mitogen-induced activation of pp70s6k, a mitogen-regulated serine/threonine kinase involved in the G1 to S phase transition of the cell cycle

Key facts & specifications
Also known as
N-p-Tosyl-L-phenylalanine chloromethyl ketone
Molecular weight
351.80
Form / buffer
powder
Activity
TPCK is an irreversible inhibitor of the serine protease chymotrypsin. It also inhibits certain cysteine proteases (bromelain, ficin, papain). TPCK inhibited (IC50 = 5 µM) the mitogen-induced activation of pp70s6k, a mitogen-regulated serine/threonine kinase involved in the G1 to S phase transition of the cell cycle.
Molecular formula
C 17 H 18 ClNO 3 S
Solubility
Soluble in DMSO (up to 10 mg/ml).
Technical note
Stability: ≥ 1 year.
Identifiers & database references
Manufacturer SKU
TBI2290-500MG
CAS number
402-71-1
Storage, stability & shipping
Storage conditions
-20°C
Shipped at
4°C
Long-term storage
-20°C
Compliance & documents
Datasheet
Open datasheet
Safety data sheet
Open SDS
Frequently asked questions
Who manufactured this product?

This product is manufactured by TriBio Science and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

TriBio Science
£163.00