Manufactured by:TriBio Science
RUO

Ranolazine, Selective sodium channel blocker

Ranolazine is an FDA-approved drug used for the treatment of chronic angina. It inhibits the late inward sodium current in heart muscle leading to decreased intracellular calcium levels. It blocks Nav 1.4, 1.5, 1.7 and 1.8 (IC50’s = 2.42, 6.22, 1.72(10.33), 21.53 µM respectively

SKU:
ABM148635-1
Manufacturer SKU
TBI3701-10MG | TBI3701-50MG
Product type
Biochemical Inhibitors
Targetsodium channel blocker
Purity>98%

Manufacturer provenance

Manufactured by:
TriBio Science
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

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Product description

Ranolazine is an FDA-approved drug used for the treatment of chronic angina. It inhibits the late inward sodium current in heart muscle leading to decreased intracellular calcium levels. It blocks Nav 1.4, 1.5, 1.7 and 1.8 (IC50’s = 2.42, 6.22, 1.72(10.33), 21.53 µM respectively

Key facts & specifications
Also known as
(±)-N-(2,6-Dimethylphenyl)-2-[4-[2-hydroxy-3-(2-methoxyphenoxy)-propyl]piperazin-1-yl]acetamide
Molecular weight
427.54
Form / buffer
powder
Activity
Ranolazine is an FDA-approved drug used for the treatment of chronic angina. It inhibits the late inward sodium current in heart muscle leading to decreased intracellular calcium levels. It blocks Nav 1.4, 1.5, 1.7 and 1.8 (IC50’s = 2.42, 6.22, 1.72(10.33), 21.53 µM respectively.
Molecular formula
C 24 H 33 N 3 O 4
Solubility
Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 20 mg/ml).
Technical note
Stability: ≥ 1 year.
Identifiers & database references
Manufacturer SKU
TBI3701-10MG | TBI3701-50MG
CAS number
142387-99-3
Storage, stability & shipping
Storage conditions
RT
Shipped at
4°C
Long-term storage
RT
Compliance & documents
Datasheet
Open datasheet
Frequently asked questions
Who manufactured this product?

This product is manufactured by TriBio Science and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

TriBio Science
£49.00