Manufactured by:TriBio Science
RUO

R-59022, DAG kinase inhibitor

R-59022 is a diacylglycerol kinase (DAGK) inhibitor, nonselective for DAGK isotypes (IC50=2.8 µM in intact platelets). Induces autophagy and apoptosis in NG108-15 neuronal cells via an mTOR-independent mechanism. Prevents conjugated linoleic acid-mediated inflammatory signaling and insulin...

SKU:
ABM148630-1
Manufacturer SKU
TBI3579-25MG | TBI3579-5MG
Product type
Biochemical Inhibitors
TargetDAG kinase
Purity>98%

Manufacturer provenance

Manufactured by:
TriBio Science
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

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Product description

R-59022 is a diacylglycerol kinase (DAGK) inhibitor, nonselective for DAGK isotypes (IC50=2.8 µM in intact platelets). Induces autophagy and apoptosis in NG108-15 neuronal cells via an mTOR-independent mechanism. Prevents conjugated linoleic acid-mediated inflammatory signaling and insulin resistance in human adipocytes. Blocks filovirus internalization in host cells

Key facts & specifications
Also known as
Diacylglycerol kinase inhibitor i
Molecular weight
459.6
Form / buffer
powder
Activity
R-59022 is a diacylglycerol kinase (DAGK) inhibitor, nonselective for DAGK isotypes (IC50=2.8 µM in intact platelets). Induces autophagy and apoptosis in NG108-15 neuronal cells via an mTOR-independent mechanism. Prevents conjugated linoleic acid-mediated inflammatory signaling and insulin resistance in human adipocytes. Blocks filovirus internalization in host cells.
Molecular formula
C 27 H 26 FN 3 OS
Solubility
Soluble in DMSO (up to 25 mg/ml)
Technical note
Stability: ≥ 2 years.
Identifiers & database references
Manufacturer SKU
TBI3579-25MG | TBI3579-5MG
CAS number
93076-89-2
Storage, stability & shipping
Storage conditions
-20°C
Shipped at
4°C
Long-term storage
-20°C
Compliance & documents
Datasheet
Open datasheet
Frequently asked questions
Who manufactured this product?

This product is manufactured by TriBio Science and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

TriBio Science
£441.00