Atypical antipsychotic agent. Antagonist at serotonin (5-HT2) and dopamine (D2) receptors, IC50s=148 and 329 nM respectively. Reverses depressive-like behavior and reduces DNA methyltransferase activity induced by maternal deprivation in a rat model. Efficacious as a monotherapy in the treatment...
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Atypical antipsychotic agent. Antagonist at serotonin (5-HT2) and dopamine (D2) receptors, IC50s=148 and 329 nM respectively. Reverses depressive-like behavior and reduces DNA methyltransferase activity induced by maternal deprivation in a rat model. Efficacious as a monotherapy in the treatment of posttraumatic stress disorder
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