Mouse C5a ELISA Kit is a research-use solid-phase ELISA for quantitative measurement of C5a. Complement component C5a is a multifunctional proinfammatory mediator produced by complement cascade activation and causes inflammatory responses and cytokine production in septic shock, allergy, trauma,...
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Mouse C5a ELISA Kit is a research-use solid-phase ELISA for quantitative measurement of C5a.
Complement component C5a is a multifunctional proinfammatory mediator produced by complement cascade activation and causes inflammatory responses and cytokine production in septic shock, allergy, trauma, ischemic heart disease, pain, neurodegenerative diseases and several other autoimmune diseases
Complement component C5a is a multifunctional proinflammatory mediator produced by complement cascade activation and causes inflammatory responses and cytokine production in septic shock, allergy, trauma, ischemic heart disease, pain, neurodegenerative diseases, and several other autoimmune diseases. C5a is rapidly cleaved to the C5a-DesArg form by the endogenous serum carboxypeptidase enzyme
Fully tested in-house by ABMIUM, or supported by an advanced validation report from a partner reviewed by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Sample compatibility evidence using the same validation key.
| Sample type | Sample compatibility |
|---|---|
| Serum |
This product is manufactured by TriBio Science and sold through ABMIUM without relabelling.
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Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.
C5 (complement C5) is a complement-system precursor cleaved into C5a and C5b, coupling complement activation to inflammatory signalling and membrane attack complex assembly.
Biological function: C5 convertases cleave complement C5 to generate C5a and C5b. C5a is a potent anaphylatoxin and chemoattractant that drives inflammatory leukocyte responses, whereas C5b initiates assembly of the terminal complement complex with C6-C9, leading to membrane attack complex formation.
