mTOR activator. Suppresses autophagy by inhibiting the fusion of autophagosomes with lysosomes leading to the accumulation of enlarged autophagosomes. Increases ovarian follicle development. Displays cellular protective effects from cytotoxic doses of dexamethasone or UV radiation. A useful tool...
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mTOR activator. Suppresses autophagy by inhibiting the fusion of autophagosomes with lysosomes leading to the accumulation of enlarged autophagosomes. Increases ovarian follicle development. Displays cellular protective effects from cytotoxic doses of dexamethasone or UV radiation. A useful tool for probing the cellular role of mTOR. Cell permeable
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Mechanistic target of rapamycin kinase (MTOR), commonly called mTOR, is a serine/threonine protein kinase and core component of mTOR signalling complexes. This ABMIUM record connects NCBI Gene 2475 and UniProtKB P42345 to catalogue-backed research products.
Biological function: Mechanistic target of rapamycin kinase (mTOR/MTOR) is the catalytic kinase of mTORC1 and mTORC2. These complexes integrate nutrient, energy and growth-factor signals to regulate processes including protein synthesis, cell growth, metabolism, survival and cytoskeletal organisation.
