Manufactured by:TriBio Science
RUO

ICA-121431, Nav1.1/1.3 inhibitor (selective)

selective Nav1.1/1.3 inhibitor (hIC50s = 23 and 13 nM respectively; also selective for dog, monkey, and mouse, but not rat). It exclusively shifts voltage dependence to more negative voltages and accelerates entry into slow activation

SKU:
ABM147159-1
Manufacturer SKU
TBI4085-25MG | TBI4085-5MG
Product type
Biochemical Inhibitors
TargetNav1.1/1.3 ()
Purity>98%

Manufacturer provenance

Manufactured by:
TriBio Science
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

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Product description

selective Nav1.1/1.3 inhibitor (hIC50s = 23 and 13 nM respectively; also selective for dog, monkey, and mouse, but not rat). It exclusively shifts voltage dependence to more negative voltages and accelerates entry into slow activation

Key facts & specifications
Also known as
2,2-Diphenyl-N-[4-(1,3-thiazol-2-ylsulfamoyl)phenyl]acetamide
Molecular weight
449.54
Form / buffer
powder
Activity
selective Nav1.1/1.3 inhibitor (hIC50s = 23 and 13 nM respectively; also selective for dog, monkey, and mouse, but not rat). It exclusively shifts voltage dependence to more negative voltages and accelerates entry into slow activation.
Molecular formula
C 23 H 19 N 3 O 3 S 2
Solubility
Soluble in DMSO (up to 25 mg/ml)
Technical note
Stability: ≥ 2 years.
Identifiers & database references
Manufacturer SKU
TBI4085-25MG | TBI4085-5MG
CAS number
313254-51-2
Storage, stability & shipping
Storage conditions
-20°C
Shipped at
4°C
Long-term storage
-20°C
Compliance & documents
Datasheet
Open datasheet
Safety data sheet
Open SDS
Frequently asked questions
Who manufactured this product?

This product is manufactured by TriBio Science and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

TriBio Science
£286.00