Manufactured by:TriBio Science
RUO

GW-9662, PPARg antagonist

Selective PPARγ antagonist (IC50 = 3.3, 32 and 2000 nM for PPARγ, PPARα and PPARδ respectively). Blocks the inhibition of osteoclast formation induced by IL-4 (1-2 μM). Displays anticancer activity inhibits growth of human mammary tumor cell lines. A useful tool for dissecting the involvement of...

SKU:
ABM147118-1
Manufacturer SKU
TBI2622-10MG | TBI2622-50MG
Product type
Biochemical Inhibitors
TargetPPARg
Purity>98%

Manufacturer provenance

Manufactured by:
TriBio Science
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

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Product description

Selective PPARγ antagonist (IC50 = 3.3, 32 and 2000 nM for PPARγ, PPARα and PPARδ respectively). Blocks the inhibition of osteoclast formation induced by IL-4 (1-2 μM). Displays anticancer activity inhibits growth of human mammary tumor cell lines. A useful tool for dissecting the involvement of PPARγ in cellular physiology

Key facts & specifications
Also known as
2-Chloro-5-nitrobenzanilide
Molecular weight
276.68
Form / buffer
powder
Activity
Selective PPARγ antagonist (IC50 = 3.3, 32 and 2000 nM for PPARγ, PPARα and PPARδ respectively). Blocks the inhibition of osteoclast formation induced by IL-4 (1-2 μM). Displays anticancer activity inhibits growth of human mammary tumor cell lines. A useful tool for dissecting the involvement of PPARγ in cellular physiology.
Molecular formula
C 13 H 9 ClN 2 O 3
Solubility
Soluble in DMSO (up to 50 mg/ml) or in Ethanol (up to 10 mg/ml).
Technical note
Stability: ≥ 2 years.
Identifiers & database references
Manufacturer SKU
TBI2622-10MG | TBI2622-50MG
CAS number
22978-25-2
Storage, stability & shipping
Storage conditions
RT
Shipped at
4°C
Long-term storage
RT
Compliance & documents
Datasheet
Open datasheet
Frequently asked questions
Who manufactured this product?

This product is manufactured by TriBio Science and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

Research target context

PPARGperoxisome proliferator activated receptor gamma

View target guide

PPARG identifies peroxisome proliferator activated receptor gamma in Homo sapiens (Human). This target record connects NCBI Gene 5468, UniProtKB P37231 and related ABMIUM catalogue products.

Organism
Multiple species; representative: Homo sapiens (Human)
NCBI Gene
5468
UniProtKB
P37231
TriBio Science
£74.00