Platelet-activating factor (PAF) receptor antagonist (Ki = 1.3 μM). Inhibits neutrophil degranulation and superoxide production in vitro. Inhibits PAF-induced bronchoconstriction in a guinea pig model. Displays neuroprotective effects in various models. Protects against focal cerebral ischemia...
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Platelet-activating factor (PAF) receptor antagonist (Ki = 1.3 μM). Inhibits neutrophil degranulation and superoxide production in vitro. Inhibits PAF-induced bronchoconstriction in a guinea pig model. Displays neuroprotective effects in various models. Protects against focal cerebral ischemia via inhibition of the mitochondrial apoptotic pathway
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