Manufactured by:TriBio Science
RUO

Exo2, GBF1 inhibitor; Induces Golgi disassembly

Exo2 disrupts the Golgi apparatus and stimulates Golgi-ER fusion in mammalian cells. May be used to completely ablate the Golgi apparatus. Like brefeldin A (BFA), it inhibits anterograde transport and disrupts morphology of the trans-Golgi network (TGN) but unlike BFA, it does not induce...

SKU:
ABM147009-1
Manufacturer SKU
TBI1594-25MG | TBI1594-5MG
Product type
Biochemical Inhibitors
TargetGBF1 ; Induces Golgi disassembly
Purity>98%

Manufacturer provenance

Manufactured by:
TriBio Science
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

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Product description

Exo2 disrupts the Golgi apparatus and stimulates Golgi-ER fusion in mammalian cells. May be used to completely ablate the Golgi apparatus. Like brefeldin A (BFA), it inhibits anterograde transport and disrupts morphology of the trans-Golgi network (TGN) but unlike BFA, it does not induce tubulation and merging of the TGN and endosomal compartments. It perturbs trafficking of Shiga toxin between endosomes and the trans-Golgi network, in contrast to cholera toxin. Accelerates degradation of perilipin-2 proteins

Key facts & specifications
Also known as
2-Methoxy-4-[(5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-4-yl)-hydrazonomethyl]-phenol
Molecular weight
354.43
Form / buffer
powder
Activity
Exo2 disrupts the Golgi apparatus and stimulates Golgi-ER fusion in mammalian cells. May be used to completely ablate the Golgi apparatus. Like brefeldin A (BFA), it inhibits anterograde transport and disrupts morphology of the trans-Golgi network (TGN) but unlike BFA, it does not induce tubulation and merging of the TGN and endosomal compartments. It perturbs trafficking of Shiga toxin between endosomes and the trans-Golgi network, in contrast to cholera toxin. Accelerates degradation of perilipin-2 proteins.
Molecular formula
C 18 H 18 N 4 O 2 S
Solubility
Soluble in DMSO (up to 25 mg/ml)
Technical note
Stability: ≥ 1 year.
Identifiers & database references
Manufacturer SKU
TBI1594-25MG | TBI1594-5MG
CAS number
304684-77-3
Storage, stability & shipping
Storage conditions
-20°C
Shipped at
4°C
Long-term storage
-20°C
Compliance & documents
Datasheet
Open datasheet
Frequently asked questions
Who manufactured this product?

This product is manufactured by TriBio Science and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

TriBio Science
£405.00