Liver-targeted antiapoptotic pan-caspase inhibitor. It has been investigated as a hepatoprotective agent in the treatment of liver ischemia and NASH/NAFLD liver injury. Emricasan protected SNB-19 cells against cell death induced by Zika virus strains MR766, FSS13025, and PRVABC59. Emricasan...
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Liver-targeted antiapoptotic pan-caspase inhibitor. It has been investigated as a hepatoprotective agent in the treatment of liver ischemia and NASH/NAFLD liver injury. Emricasan protected SNB-19 cells against cell death induced by Zika virus strains MR766, FSS13025, and PRVABC59. Emricasan improves the viability of hPSCs and their differentiated progeny when used in a small molecule cocktail (CEPT) containing chroman 1, polyamines and trans-ISRIB
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