A potent and selective HDAC3 inhibitor (IC50 = 289 nM), IC50s for HDAC1, 2 and 6 = 2, 2.2 and >20 µM respectively. Inhibits tumor growth in a mouse xenograft model of human multiple myeloma. Downregulates expression of DNA methyltransferase 1. Increases expression of synaptic proteins in...
Know who made it. See the evidence. Buy through one marketplace.
A potent and selective HDAC3 inhibitor (IC50 = 289 nM), IC50s for HDAC1, 2 and 6 = 2, 2.2 and >20 µM respectively. Inhibits tumor growth in a mouse xenograft model of human multiple myeloma. Downregulates expression of DNA methyltransferase 1. Increases expression of synaptic proteins in exogenous Aβ-treated cells and mice. Rescues synaptic damage and neuron loss in APP-transfected cells (15 µM) and APP/PS1 mice (30 mg/kg)
This product is manufactured by TriBio Science and sold through ABMIUM without relabelling.
ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.
Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.
