Vanilloid receptor I (TRPV1) antagonist, IC 50 = 35 nM for capsaicin-induced and 6 nM for acid-induced TRPV1 activation. Displays analgesic activity in rat models of neuropathic pain. Orally active and cell permeable Solutions in DMSO or ethanol may be stord at -20°C for up to 2 months
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Vanilloid receptor I (TRPV1) antagonist, IC 50 = 35 nM for capsaicin-induced and 6 nM for acid-induced TRPV1 activation. Displays analgesic activity in rat models of neuropathic pain. Orally active and cell permeable
Solutions in DMSO or ethanol may be stord at -20°C for up to 2 months
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