A structurally novel, potent inhibitor of receptor tyrosine kinases inhibiting VEGFR and PDGFR and related kinases with IC 50 s = 3, 4, 4, 66, 3 and 14 nM for VEGFR1, VEGFR2, FLT3, PDGFRβ, CSF-1R and KIT respectively. Protects cells from necroptosis and rescues SIRS mice from TNF-α-induced shock...
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A structurally novel, potent inhibitor of receptor tyrosine kinases inhibiting VEGFR and PDGFR and related kinases with IC 50 s = 3, 4, 4, 66, 3 and 14 nM for VEGFR1, VEGFR2, FLT3, PDGFRβ, CSF-1R and KIT respectively. Protects cells from necroptosis and rescues SIRS mice from TNF-α-induced shock and death. Exerts anti-obesity effects by promoting adipocyte browning. Inhibits angiogenesis
This product is manufactured by TriBio Science and sold through ABMIUM without relabelling.
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