Manufactured by:Reed Biotech
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PKC ζ Polyclonal Antibody

PKC ζ polyclonal antibody; host Rabbit; reactivity Human, Mouse, Rat, Monkey

SKU:
ABM5033213-1
Manufacturer SKU
RA28819
Product type
Primary Antibodies
TargetPKC ζ
ApplicationsWB, IHC-P, ICC/IF, ELISA
Species / reactivityHuman, Mouse, Rat, Monkey

Manufacturer provenance

Manufactured by:
Reed Biotech
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

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Product description

protein kinase C zeta(PRKCZ) Homo sapiens Protein kinase C (PKC) zeta is a member of the PKC family of serine/threonine kinases which are involved in a variety of cellular processes such as proliferation, differentiation and secretion. Unlike the classical PKC isoenzymes which are calcium-dependent, PKC zeta exhibits a kinase activity which is independent of calcium and diacylglycerol but not of phosphatidylserine. Furthermore, it is insensitive to typical PKC inhibitors and cannot be activated by phorbol ester. Unlike the classical PKC isoenzymes, it has only a single zinc finger module. These structural and biochemical properties indicate that the zeta subspecies is related to, but distinct from other isoenzymes of PKC. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008],

Key facts & specifications
Also known as
PRKCZ, PKC2, Protein kinase C zeta type, nPKC-zeta
Host species
Rabbit
Clonality
Polyclonal
Dilution range
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.
Immunogen
The antiserum was produced against synthesized peptide derived from human PKC zeta. AA range:526-575
Molecular weight
80 kDa
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form / buffer
Liquid
Quantity per pack
50 or 100 µL
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Manufacturer-listed application compatibility

Evidence status by application and model.

Species / reactivityWBIHC-PIF/ICCELISA
Human,Mouse,Rat,Monkey
Identifiers & database references
Manufacturer SKU
RA28819
Gene ID
5590
UniProt accession
Q05513
Storage, stability & shipping
Storage conditions
-20°C/1 year
Long-term storage
-20°C/1 year
Storage buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Compliance & documents
Datasheet
Open datasheet
Product manual
Open manual
Frequently asked questions
Who manufactured this product?

This product is manufactured by Reed Biotech and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

Reed Biotech
£189.00£113.40