Manufactured by:Reed Biotech
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HIF-1 β/ARNT Monoclonal Antibody (4C5)

HIF-1 β/ARNT monoclonal antibody; host Mouse; reactivity Mouse

SKU:
ABM5042200-1
Manufacturer SKU
RA11370
Product type
Primary Antibodies
TargetHIF-1 β/ARNT
ApplicationsWB, IHC-P, IF
Species / reactivityMouse

Manufacturer provenance

Manufactured by:
Reed Biotech
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

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Product description

aryl hydrocarbon receptor nuclear translocator(ARNT) Homo sapiens This gene encodes a protein containing a basic helix-loop-helix domain and two characteristic PAS domains along with a PAC domain. The encoded protein binds to ligand-bound aryl hydrocarbon receptor and aids in the movement of this complex to the nucleus, where it promotes the expression of genes involved in xenobiotic metabolism. This protein is also a co-factor for transcriptional regulation by hypoxia-inducible factor 1. Chromosomal translocation of this locus with the ETV6 (ets variant 6) gene on chromosome 12 have been described in leukemias. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2013],

Key facts & specifications
Also known as
ARNT, BHLHE2, Aryl hydrocarbon receptor nuclear translocator, ARNT protein, Class E basic helix-loop-helix protein 2, Dioxin receptor, nuclear translocator, Hypoxia-inducible factor 1-beta, HIF-1-beta, HIF1-beta
Host species
Mouse
Clonality
Monoclonal
Clone number
4C5
Dilution range
WB 1:1000-2000, IHC 1:100-200
Immunogen
Recombinant Protein of HIF-1 β
Molecular weight
87 kDa
Purification
The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
Form / buffer
Liquid
Quantity per pack
50 or 100 µL
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Manufacturer-listed application compatibility

Evidence status by application and model.

Species / reactivityWBIHC-PIF
Mouse
Identifiers & database references
Manufacturer SKU
RA11370
Gene ID
405
UniProt accession
P27540
Storage, stability & shipping
Storage conditions
-20°C/1 year
Long-term storage
-20°C/1 year
Storage buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Compliance & documents
Datasheet
Open datasheet
Product manual
Open manual
Frequently asked questions
Who manufactured this product?

This product is manufactured by Reed Biotech and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

Reed Biotech
£189.00£113.40