Manufactured by:Reed Biotech
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CYP2E1 Polyclonal Antibody

CYP2E1 polyclonal antibody; host Rabbit; reactivity Human, Mouse, Rat

SKU:
ABM5025373-1
Manufacturer SKU
RA20979
Product type
Primary Antibodies
TargetCYP2E1
ApplicationsWB, IHC-P, IF/ICC, ELISA
Species / reactivityHuman, Mouse, Rat

Manufacturer provenance

Manufactured by:
Reed Biotech
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

Know who made it. See the evidence. Buy through one marketplace.

Product description

cytochrome P450 family 2 subfamily E member 1(CYP2E1) Homo sapiens This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is induced by ethanol, the diabetic state, and starvation. The enzyme metabolizes both endogenous substrates, such as ethanol, acetone, and acetal, as well as exogenous substrates including benzene, carbon tetrachloride, ethylene glycol, and nitrosamines which are premutagens found in cigarette smoke. Due to its many substrates, this enzyme may be involved in such varied processes as gluconeogenesis, hepatic cirrhosis, diabetes, and cancer. [provided by RefSeq, Jul 2008],

Key facts & specifications
Also known as
CYP2E1, CYP2E, Cytochrome P450 2E1, 4-nitrophenol 2-hydroxylase, CYPIIE1, Cytochrome P450-J
Host species
Rabbit
Clonality
Polyclonal
Dilution range
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.
Immunogen
The antiserum was produced against synthesized peptide derived from human Cytochrome P450 2E1. AA range:371-420
Molecular weight
56 kDa
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form / buffer
Liquid
Quantity per pack
50 or 100 µL
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Manufacturer-listed application compatibility

Evidence status by application and model.

Species / reactivityWBIHC-PIF/ICCELISA
Human,Mouse,Rat
Identifiers & database references
Manufacturer SKU
RA20979
Gene ID
1571
UniProt accession
P05181
Storage, stability & shipping
Storage conditions
-20°C/1 year
Long-term storage
-20°C/1 year
Storage buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Compliance & documents
Datasheet
Open datasheet
Product manual
Open manual
Frequently asked questions
Who manufactured this product?

This product is manufactured by Reed Biotech and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

Research target context

CYP2E1cytochrome P450 family 2 subfamily E member 1

View target guide

CYP2E1 identifies cytochrome P450 family 2 subfamily E member 1 in Homo sapiens (Human). This target record connects NCBI Gene 1571, UniProtKB P05181 and related ABMIUM catalogue products.

Organism
Multiple species; representative: Homo sapiens (Human)
NCBI Gene
1571
UniProtKB
P05181
Reed Biotech
£189.00£113.40