Rat RANK ELISA Kit PicoKine®

Rat RANK ELISA Kit PicoKine® (96 Tests). Quantitate Rat Tnfrsf11a in cell culture supernatants and serum. Sensitivity: 10pg/ml. The brand Picokine indicates this is a premium quality ELISA kit. Each Picokine kit delivers precise quantification, high sensitivity, and excellent reproducibility. Only our most reliable and effective kits qualify as Picokine, guaranteeing top-tier results for your assays.

Receptor Activator of Nuclear Factor κ B (RANK), also known as TRANCE Receptor, is a type I membrane protein that is expressed on the surface of osteoclasts and is involved in their activation upon ligand binding. RANK is a recently described TNF receptor family member, and its ligand, RANKL, promote survival of dendritic cells and differentiation of osteoclasts. RANK contains 383 amino acids in its intracellular domain (residues 234-616), which contain three putative TRAF-binding domains (termed I, II, and III). RANK interacts with various TRAFs through distinct motifs and activates NF-kappaB via a novel TRAF6 interaction motif, which then activates NIK, thus leading to NF-kappaB activation, whereas RANK most likely activates JNK through a TRAF2-interacting region in RANK. The standard in this kit is recombinant human RANK with the sequence of Q29-G213 aa. It is a dipolymer which compose of two chains, and the molecular weight of each is 48kda.

Product information

Supplier	Boster Bio
ABMIUM evidence status	ABMIUM Verified™ collaborator-tested data
Catalogue reference	EK1281
Product category	PicoKine® ELISA Kits
Reactive species	Rat
Tested applications	ELISA
Gene name	TNFRSF11A
Protein name	TNF receptor superfamily member 11A
Sample type	cell culture supernatants and serum.
Assay range	62.5 pg/ml - 4,000 pg/ml
Sensitivity	<10 pg/ml
Specificity	Natural and recombinant rat RANK
Immunogen	Expression system for standard: NS0; Immunogen sequence: Q30-P213
Storage	Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)
UniProt	F1M8Z6
NCBI Gene ID	498206

Available variants

Conjugation	Size
Not applicable	96 wells/kit, with removable strips.