Manufactured by:Promab
RUO

Anti-TXK (N-term) Rabbit Polyclonal Antibody

TXK (N-term) antibody from Promab.

SKU:
ABM417250-1
Product type
Primary antibodies
TargetTXK (N-term)
ApplicationsWB
Species / reactivityHuman

Manufacturer provenance

Manufactured by:
Promab
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

Know who made it. See the evidence. Buy through one marketplace.

Product description

Non-receptor tyrosine kinase that plays a redundant role with ITK in regulation of the adaptive immune response. TXK regulates the development, function and differentiation of conventional T-cells and nonconventional NKT-cells. When antigen presenting cells (APC) activate T-cell receptor (TCR), a series of phosphorylation leads to the recruitment of TXK to the cell membrane, where it is phosphorylated at Tyr-420.

For research use only.

Key facts & specifications
Also known as
Tyrosine-protein kinase TXK; Protein-tyrosine kinase 4; Resting lymphocyte kinase; TXK; PTK4; RLK; TXK tyrosine kinase; TXK (N-term)
Host species
Rabbit
Clonality
Polyclonal
Conjugation
Unconjugated
Immunogen
This TXK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 22-52 amino acids from the N-terminal region of human TXK.
Molecular weight
61.3 kDa
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Application matrix

Evidence status by application and model.

SpeciesWBIHCIHC-PIHC-FIF/ICCFlow CytometryELISAIPChIP
Human
Identifiers & database references
Gene symbol
TXK
Gene ID
7294
UniProt accession
P42681
Ensembl
ENSG00000074966
HGNC
12434
OMIM
600058
Storage, stability & shipping
Short-term storage
4°C (short term)
Long-term storage
-20°C (long term); aliquot and avoid repeated freeze-thaw cycles
Storage buffer
Purified antibody in PBS with 0.05% sodium azide,1%BSA and 50% glycerol.prepared by Saturated Ammonium Sulfate (SAS) .
Aliquoting guidance
Aliquot to avoid repeated freeze-thaw.
Compliance & documents
CE marked
No
Frequently asked questions
Who manufactured this product?

This product is manufactured by Promab and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

Promab
£174.20