Manufactured by:Promab
RUO

Anti-TDG Rabbit Polyclonal Antibody

TDG antibody from Promab.

SKU:
ABM421215-1
Product type
Primary antibodies
TargetTDG
ApplicationsWB, IHC, IF/ICC
Species / reactivityHuman, Mouse, Rat, Bovine

Manufacturer provenance

Manufactured by:
Promab
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

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Product description

DNA glycosylase that plays a key role in active DNA demethylation: specifically recognizes and binds 5-formylcytosine (5fC) and 5-carboxylcytosine (5caC) in the context of CpG sites and mediates their excision through base-excision repair (BER) to install an unmethylated cytosine. Cannot remove 5-hydroxymethylcytosine (5hmC). According to an alternative model, involved in DNA demethylation by mediating DNA glycolase activity toward 5-hydroxymethyluracil (5hmU) produced by deamination of 5hmC.

For research use only.

Key facts & specifications
Also known as
G/T mismatch-specific thymine DNA glycosylase; Thymine-DNA glycosylase; hTDG; TDG
Host species
Rabbit
Clonality
Polyclonal
Conjugation
Unconjugated
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human Thymine DNA Glycosylase. The exact sequence is proprietary.
Molecular weight
46 kD
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Application matrix

Evidence status by application and model.

SpeciesWBIHCIHC-PIHC-FIF/ICCFlow CytometryELISAIPChIP
Human
Mouse
Rat
Bovine
Identifiers & database references
Gene symbol
TDG
Gene ID
6996
UniProt accession
Q13569
Ensembl
ENSG00000139372
HGNC
11700
OMIM
601423
Storage, stability & shipping
Short-term storage
4°C (short term)
Long-term storage
-20°C (long term); aliquot and avoid repeated freeze-thaw cycles
Aliquoting guidance
Aliquot to avoid repeated freeze-thaw.
Compliance & documents
CE marked
No
Frequently asked questions
Who manufactured this product?

This product is manufactured by Promab and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

Promab
£174.20