Manufactured by:Promab
RUO

Anti-SDF1 Rabbit Polyclonal Antibody

SDF1 antibody from Promab.

SKU:
ABM413261-1
Product type
Primary antibodies
TargetSDF1
ApplicationsWB, IHC, IF/ICC
Species / reactivityHuman, Mouse, Rat

Manufacturer provenance

Manufactured by:
Promab
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

Know who made it. See the evidence. Buy through one marketplace.

Product description

Chemoattractant active on T-lymphocytes and monocytes but not neutrophils. Activates the C-X-C chemokine receptor CXCR4 to induce a rapid and transient rise in the level of intracellular calcium ions and chemotaxis. Also binds to atypical chemokine receptor ACKR3, which activates the beta-arrestin pathway and acts as a scavenger receptor for CXCL12/SDF-1.

For research use only.

Key facts & specifications
Also known as
CXCL12; SDF1; SDF1A; SDF1B; Stromal cell-derived factor 1; hSDF-1; C-X-C motif chemokine 12; Intercrine reduced in hepatomas; IRH; hIRH; Pre-B cell growth-stimulating factor; PBSF; C-X-C motif chemokine ligand 12
Host species
Rabbit
Clonality
Polyclonal
Conjugation
Unconjugated
Immunogen
The antiserum was produced against synthesized peptide derived from human SDF-1. AA range:44-93
Molecular weight
Calculated MW: 11 kDa; Observed MW: 11 kDa
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Application matrix

Evidence status by application and model.

SpeciesWBIHCIHC-PIHC-FIF/ICCFlow CytometryELISAIPChIP
Human
Mouse
Rat
Identifiers & database references
Gene symbol
CXCL12
Gene ID
6387
UniProt accession
P48061
Ensembl
ENSG00000107562
HGNC
10672
OMIM
600835
Storage, stability & shipping
Short-term storage
4°C (short term)
Long-term storage
-20°C (long term); aliquot and avoid repeated freeze-thaw cycles
Storage buffer
Purified antibody in PBS with 0.05% sodium azide,0.5%BSA and 50% glycerol.
Aliquoting guidance
Aliquot to avoid repeated freeze-thaw.
Compliance & documents
CE marked
No
Frequently asked questions
Who manufactured this product?

This product is manufactured by Promab and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

Research target context

CXCL12C-X-C motif chemokine ligand 12

View target guide

C-X-C motif chemokine ligand 12 (CXCL12), widely known as stromal cell-derived factor 1 (SDF-1), is a chemokine central to chemotaxis and cell trafficking. This hub connects verified names and identifiers with ABMIUM catalogue products.

Biological function: C-X-C motif chemokine ligand 12 (CXCL12/SDF-1) is a chemoattractant for T lymphocytes and monocytes. Reviewed UniProt evidence shows signalling through CXCR4 to induce calcium responses and chemotaxis, with additional binding to the atypical chemokine receptor ACKR3.

Organism
Multiple species; representative: Homo sapiens (Human)
NCBI Gene
6387
UniProtKB
P48061
Promab
£174.20