Manufactured by:Promab
RUO

Anti-PABPC1 Rabbit Polyclonal Antibody

PABPC1 antibody from Promab.

SKU:
ABM413647-1
Product type
Primary antibodies
TargetPABPC1
ApplicationsWB, IHC-P
Species / reactivityHuman, Mouse

Manufacturer provenance

Manufactured by:
Promab
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

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Product description

PABPC1 binds the poly(A) tail of mRNA, including that of its own transcript, and regulates processes of mRNA metabolism such as pre-mRNA splicing and mRNA stability. Its function in translational initiation regulation can either be enhanced by PAIP1 or repressed by PAIP2. PABPC1 can probably bind to cytoplasmic RNA sequences other than poly(A) in vivo.

For research use only.

Key facts & specifications
Also known as
Polyadenylate-binding protein 1; PABP-1; Poly(A)-binding protein 1; PABPC1; PAB1; PABPC2; poly(A) binding protein cytoplasmic 1
Host species
Rabbit
Clonality
Polyclonal
Conjugation
Unconjugated
Immunogen
This PABPC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 250-279 amino acids from the Central region of human PABPC1.
Molecular weight
70.7 kDa
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Application matrix

Evidence status by application and model.

SpeciesWBIHCIHC-PIHC-FIF/ICCFlow CytometryELISAIPChIP
Human
Mouse
Identifiers & database references
Gene symbol
PABPC1
Gene ID
26986
UniProt accession
P11940
Ensembl
ENSG00000070756
HGNC
8554
OMIM
604679
Storage, stability & shipping
Short-term storage
4°C (short term)
Long-term storage
-20°C (long term); aliquot and avoid repeated freeze-thaw cycles
Storage buffer
Purified antibody in PBS with 0.05% sodium azide,1%BSA and 50% glycerol.prepared by Saturated Ammonium Sulfate (SAS) .
Aliquoting guidance
Aliquot to avoid repeated freeze-thaw.
Compliance & documents
CE marked
No
Frequently asked questions
Who manufactured this product?

This product is manufactured by Promab and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

Promab
£174.20