Manufactured by:Promab
RUO

Anti-MEX3C Rabbit Polyclonal Antibody

MEX3C antibody from Promab.

SKU:
ABM415455-1
Product type
Primary antibodies
TargetMEX3C
ApplicationsWB
Species / reactivityHuman

Manufacturer provenance

Manufactured by:
Promab
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

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Product description

MEX3C is an E3 ubiquitin ligase responsible for the post-transcriptional regulation of common HLA-A allotypes. MEX3C binds to the 3' UTR of HLA-A2 mRNA, and regulates its levels by promoting mRNA decay. RNA binding is sufficient to prevent translation, but ubiquitin ligase activity is required for mRNA degradation.

For research use only.

Key facts & specifications
Also known as
RNA-binding E3 ubiquitin-protein ligase MEX3C; 632-; RING finger and KH domain-containing protein 2; RING finger protein 194; MEX3C; RKHD2; RNF194; mex-3 RNA binding family member C
Host species
Rabbit
Clonality
Polyclonal
Conjugation
Unconjugated
Immunogen
This MEX3C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 536-564 amino acids from the C-terminal region of human MEX3C.
Molecular weight
69.4 kDa
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Application matrix

Evidence status by application and model.

SpeciesWBIHCIHC-PIHC-FIF/ICCFlow CytometryELISAIPChIP
Human
Identifiers & database references
Gene symbol
MEX3C
Gene ID
51320
UniProt accession
Q5U5Q3
Ensembl
ENSG00000176624
HGNC
28040
OMIM
611005
Storage, stability & shipping
Short-term storage
4°C (short term)
Long-term storage
-20°C (long term); aliquot and avoid repeated freeze-thaw cycles
Storage buffer
Purified antibody in PBS with 0.05% sodium azide.
Aliquoting guidance
Aliquot to avoid repeated freeze-thaw.
Compliance & documents
CE marked
No
Frequently asked questions
Who manufactured this product?

This product is manufactured by Promab and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

Promab
£174.20