Manufactured by:Promab
RUO

Anti-KIAA0999 Rabbit Polyclonal Antibody

KIAA0999 antibody from Promab.

SKU:
ABM414189-1
Product type
Primary antibodies
TargetKIAA0999
ApplicationsWB, Flow Cytometry
Species / reactivityHuman

Manufacturer provenance

Manufactured by:
Promab
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

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Product description

Positive regulator of mTOR signalling that functions by triggering the degradation of DEPTOR, an mTOR inhibitor. SIK3 is involved in the dynamic regulation of mTOR signalling in chondrocyte differentiation during skeletogenesis. Negatively regulates cAMP signalling pathway possibly by acting on CRTC2/TORC2 and CRTC3/TORC3.

For research use only.

Key facts & specifications
Also known as
Serine/threonine-protein kinase SIK3; Salt-inducible kinase 3; SIK-3; Serine/threonine-protein kinase QSK; KIAA0999; QSK; SIK family kinase 3
Host species
Rabbit
Clonality
Polyclonal
Conjugation
Unconjugated
Immunogen
This KIAA0999 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1233-1263 amino acids from the C-terminal region of human KIAA0999.
Molecular weight
144.9 kDa
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Application matrix

Evidence status by application and model.

SpeciesWBIHCIHC-PIHC-FIF/ICCFlow CytometryELISAIPChIP
Human
Identifiers & database references
Gene symbol
SIK3
Gene ID
23387
UniProt accession
Q9Y2K2
Ensembl
ENSG00000160584
HGNC
29165
OMIM
614776
Storage, stability & shipping
Short-term storage
4°C (short term)
Long-term storage
-20°C (long term); aliquot and avoid repeated freeze-thaw cycles
Storage buffer
Purified antibody in PBS with 0.05% sodium azide.
Aliquoting guidance
Aliquot to avoid repeated freeze-thaw.
Compliance & documents
CE marked
No
Frequently asked questions
Who manufactured this product?

This product is manufactured by Promab and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

Promab
£174.20