GRPEL1 antibody from Promab.
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Nucleotide exchange factor (NEF) for mitochondrial HSP70 (mt-HSP70/HSPA9), facilitating the release of ADP from HSPA9 to allow ATP rebinding, which is essential for the chaperone cycle. GRPEL1 functions as a component of the presequence translocase-associated motor (PAM) complex, which drives ATP-dependent import of proteins into the mitochondrial matrix. In the PAM complex, supports the HSPA9-driven pulling mechanism that translocates polypeptides through the TIM23 complex.
For research use only.
Fully tested in-house by ABMIUM, or supported by an advanced validation report from a partner reviewed by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Evidence status by application and model.
| Species | WB | IHC | IHC-P | IHC-F | IF/ICC | Flow Cytometry | ELISA | IP | ChIP |
|---|---|---|---|---|---|---|---|---|---|
| Human |
This product is manufactured by Promab and sold through ABMIUM without relabelling.
ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.
Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.