Manufactured by:Promab
RUO

Anti-GPR34 Rabbit Polyclonal Antibody

GPR34 antibody from Promab.

SKU:
ABM421118-1
Product type
Primary antibodies
TargetGPR34
ApplicationsWB
Species / reactivityHuman, Mouse, Rat, Monkey, Pig

Manufacturer provenance

Manufactured by:
Promab
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

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Product description

GPR34 is a G protein-coupled receptor of lysophosphatidylserine (LysoPS) that plays different roles in immune response. GPR34 acts a damage-sensing receptor that triggers tissue repair upon recognition of dying neutrophils. Mechanistically, apoptotic neutrophils release lysophosphatydilserine that are recognized by type 3 innate lymphoid cells (ILC3s) via GPR34, which activates downstream PI3K-AKT and RAS-ERK signalling pathways leading to STAT3 activation and IL-22 production.

For research use only.

Key facts & specifications
Also known as
Probable G-protein coupled receptor 34; GPR34; G protein-coupled receptor 34
Host species
Rabbit
Clonality
Polyclonal
Conjugation
Unconjugated
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human GPR34. The exact sequence is proprietary.
Molecular weight
44 kD
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Application matrix

Evidence status by application and model.

SpeciesWBIHCIHC-PIHC-FIF/ICCFlow CytometryELISAIPChIP
Human
Mouse
Rat
Monkey
Pig
Identifiers & database references
Gene symbol
GPR34
Gene ID
2857
UniProt accession
Q9UPC5
Ensembl
ENSG00000171659
HGNC
4490
OMIM
300241
Storage, stability & shipping
Short-term storage
4°C (short term)
Long-term storage
-20°C (long term); aliquot and avoid repeated freeze-thaw cycles
Aliquoting guidance
Aliquot to avoid repeated freeze-thaw.
Compliance & documents
CE marked
No
Frequently asked questions
Who manufactured this product?

This product is manufactured by Promab and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

Promab
£174.20