Manufactured by:Promab
RUO

Anti-FTO Rabbit Polyclonal Antibody

FTO antibody from Promab.

SKU:
ABM413070-1
Product type
Primary antibodies
TargetFTO
ApplicationsWB
Species / reactivityHuman, Mouse, Rat

Manufacturer provenance

Manufactured by:
Promab
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

Know who made it. See the evidence. Buy through one marketplace.

Product description

RNA demethylase that mediates oxidative demethylation of different RNA species, such as mRNAs, tRNAs and snRNAs, and acts as a regulator of fat mass, adipogenesis and energy homeostasis. Specifically demethylates N(6)-methyladenosine (m6A) RNA, the most prevalent internal modification of messenger RNA (mRNA) in higher eukaryotes. M6A demethylation by FTO affects mRNA expression and stability.

For research use only.

Key facts & specifications
Also known as
FTO; KIAA1752; Alpha-ketoglutarate-dependent dioxygenase FTO; Fat mass and obesity-associated protein; FTO alpha-ketoglutarate dependent dioxygenase
Host species
Rabbit
Clonality
Polyclonal
Conjugation
Unconjugated
Immunogen
The antiserum was produced against synthesized peptide derived from human FTO. AA range:19-68
Molecular weight
Calculated MW: 58 kDa; Observed MW: 58 kDa
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Application matrix

Evidence status by application and model.

SpeciesWBIHCIHC-PIHC-FIF/ICCFlow CytometryELISAIPChIP
Human
Mouse
Rat
Identifiers & database references
Gene symbol
FTO
Gene ID
79068
UniProt accession
Q9C0B1
Ensembl
ENSG00000140718
HGNC
24678
OMIM
610966
Storage, stability & shipping
Short-term storage
4°C (short term)
Long-term storage
-20°C (long term); aliquot and avoid repeated freeze-thaw cycles
Storage buffer
Purified antibody in PBS with 0.05% sodium azide,0.5%BSA and 50% glycerol.
Aliquoting guidance
Aliquot to avoid repeated freeze-thaw.
Compliance & documents
CE marked
No
Frequently asked questions
Who manufactured this product?

This product is manufactured by Promab and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

Research target context

FTOFTO alpha-ketoglutarate dependent dioxygenase

View target guide

FTO identifies FTO alpha-ketoglutarate dependent dioxygenase in Homo sapiens (Human). This target record connects NCBI Gene 79068, UniProtKB Q9C0B1 and related ABMIUM catalogue products.

Organism
Multiple species; representative: Homo sapiens (Human)
NCBI Gene
79068
UniProtKB
Q9C0B1
Promab
£174.20