Manufactured by:Promab
RUO

Anti-CFH Rabbit Polyclonal Antibody

CFH antibody from Promab.

SKU:
ABM417194-1
Product type
Primary antibodies
TargetCFH
ApplicationsWB
Species / reactivityHuman

Manufacturer provenance

Manufactured by:
Promab
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

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Product description

Glycoprotein that plays an essential role in maintaining a well-balanced immune response by modulating complement activation. CFH acts as a soluble inhibitor of complement, where its binding to self markers such as glycan structures prevents complement activation and amplification on cell surfaces. Accelerates the decay of the complement alternative pathway (AP) C3 convertase C3bBb, thus preventing local formation of more C3b, the central player of the complement amplification loop.

For research use only.

Key facts & specifications
Also known as
Complement factor H; H factor 1; CFH; HF; HF1; HF2
Host species
Rabbit
Clonality
Polyclonal
Conjugation
Unconjugated
Immunogen
This CFH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 751-780 amino acids of human CFH.
Molecular weight
139.1 kDa
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Application matrix

Evidence status by application and model.

SpeciesWBIHCIHC-PIHC-FIF/ICCFlow CytometryELISAIPChIP
Human
Identifiers & database references
Gene symbol
CFH
Gene ID
3075
UniProt accession
P08603
Ensembl
ENSG00000000971
HGNC
4883
OMIM
134370
Storage, stability & shipping
Short-term storage
4°C (short term)
Long-term storage
-20°C (long term); aliquot and avoid repeated freeze-thaw cycles
Storage buffer
Purified antibody in PBS with 0.05% sodium azide.
Aliquoting guidance
Aliquot to avoid repeated freeze-thaw.
Compliance & documents
CE marked
No
Frequently asked questions
Who manufactured this product?

This product is manufactured by Promab and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

Research target context

CFHcomplement factor H

View target guide

CFH identifies complement factor H in Homo sapiens (Human). This target record connects NCBI Gene 3075, UniProtKB P08603 and related ABMIUM catalogue products.

Organism
Multiple species; representative: Homo sapiens (Human)
NCBI Gene
3075
UniProtKB
P08603
Promab
£174.20