BMP2 antibody from Promab.
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BMP2 is a growth factor of the TGF-beta superfamily that plays essential roles in many developmental processes, including cardiogenesis, neurogenesis, and osteogenesis. BMP2 induces cartilage and bone formation. Initiates the canonical BMP signalling cascade by associating with type I receptor BMPR1A and type II receptor BMPR2.
For research use only.
Fully tested in-house by ABMIUM, or supported by an advanced validation report from a partner reviewed by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Evidence status by application and model.
| Species | WB | IHC | IHC-P | IHC-F | IF/ICC | Flow Cytometry | ELISA | IP | ChIP |
|---|---|---|---|---|---|---|---|---|---|
| Human | |||||||||
| Mouse | |||||||||
| Rat |
This product is manufactured by Promab and sold through ABMIUM without relabelling.
ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.
Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.
Bone morphogenetic protein 2 (BMP2/BMP-2) is a secreted TGF-beta-superfamily growth factor that drives developmental signalling, cartilage formation and osteogenic differentiation. ABMIUM catalogue products linked below support research on BMP2 biology.
Biological function: Bone morphogenetic protein 2 (BMP2) is proteolytically processed to a disulfide-linked growth-factor homodimer. It initiates canonical BMP signalling through BMP type I and type II receptor complexes, including BMPR1A and BMPR2, activating SMAD-dependent transcription. Reviewed UniProt also supports roles in cardiogenesis, neurogenesis, osteogenesis and induction of cartilage and bone formation.
