Manufactured by:ProteoGenix
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Umesolerbart Biosimilar – Anti-BETVIA mAb – Research Grade

Umesolerbart Biosimilar – Anti-BETVIA mAb – Research Grade from ProteoGenix; catalogue PX-TA2047; research use only.

SKU:
ABM134016-1
Manufacturer SKU
PX-TA2047
Product type
Primary Antibodies
TargetUmesolerbart Biosimilar – Anti-BETVIA mAb – Research Grade
ApplicationsELISA, WB
Expression systemXtenCHO
Purity>90% by SDS-PAGE.

Manufacturer provenance

Manufactured by:
ProteoGenix
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

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Product description

The Structure and Function of Umesolerbart Biosimilar – Anti-BETVIA mAb – Research Grade The

Structure of Umesolerbart Biosimilar

Umesolerbart Biosimilar is a monoclonal antibody (mAb) that has been developed as a biosimilar to the therapeutic antibody BETVIA. It is a research grade antibody that has been designed to target and bind to BETVIA, a protein that is involved in various inflammatory and autoimmune diseases.

The structure of Umesolerbart Biosimilar is similar to that of BETVIA, as it is a monoclonal antibody that is composed of two heavy chains and two light chains. These chains are connected by disulfide bonds and form a Y-shaped structure. The variable regions of the antibody, which are responsible for binding to BETVIA, are located at the tips of the Y-shaped structure.

The Activity of Umesolerbart Biosimilar

Umesolerbart Biosimilar has been specifically designed to bind to BETVIA with high affinity and specificity. This means that it has a strong and specific interaction with BETVIA, which allows it to effectively inhibit its activity.

BETVIA is a cytokine that plays a crucial role in the regulation of immune responses. It has been implicated in the development of various inflammatory and autoimmune diseases, such as rheumatoid arthritis, psoriasis, and multiple sclerosis. By targeting and binding to BETVIA, Umesolerbart Biosimilar is able to block its activity and prevent it from causing inflammation and damage in the body.

The Application of Umesolerbart Biosimilar

Umesolerbart Biosimilar has a wide range of potential applications in the field of immunology and therapeutics. Its ability to specifically target and inhibit BETVIA makes it a promising candidate for the treatment of various inflammatory and autoimmune diseases.

In pre-clinical studies, Umesolerbart Biosimilar has shown promising results in reducing inflammation and disease progression in animal models of rheumatoid arthritis and psoriasis. It has also been shown to be effective in suppressing the immune response in models of multiple sclerosis.

Furthermore, Umesolerbart Biosimilar has the potential to be used in combination with other therapies to enhance their effectiveness. For example, it could be used in combination with traditional disease-modifying antirheumatic drugs (DMARDs) in the treatment of rheumatoid arthritis.

Conclusion

In summary, Umesolerbart Biosimilar is a research grade monoclonal antibody that has been developed as a biosimilar to the therapeutic antibody BETVIA. Its structure is similar to BETVIA, and it has been designed to specifically target and bind to BETVIA with high affinity and specificity. Its potential applications in the treatment of inflammatory and autoimmune diseases make it a promising candidate for further research and development.

ProteoGenix catalogue number PX-TA2047. For research use only.

Target: Umesolerbart Biosimilar – Anti-BETVIA mAb – Research Grade; Clonality: Monoclonal Antibody; Expression system: XtenCHO; Purity: >90% by SDS-PAGE.; Buffer: 0.01M PBS, pH 7.4.; Applications: ELISA, WB.

Available configurations: 50ug, 100ug, 1mg.

Download the manufacturer datasheet

Key facts & specifications
Also known as
anti-BETVIA, Major pollen allergen Bet v 1-A, Allergen Bet v I-A, Bet v 1-A, BETVI
Clonality
Monoclonal
Isotype
IgG4-kappa
Source organism
Human
Sequence
MGVFNYETETTSVIPAARLFKAFILDGDNLFPKVAPQAISSVENIEGNGGPGTIKKISFPEGFPFKYVKDRVDEVDHTNFKYNYSVIEGGPIGDTLEKISNEIKIVATPDGGSILKISNKYHTKGDHEVKAEQVKASKEMGETLLRAVESYLLAHSDAYN
Technical note
For research use only. Not suitable for clinical or therapeutic use.
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Application validation

Evidence status by application and model.

TargetWBIHC-PIHC-FrIF/ICCFlow CytIPChIPELISA
Umesolerbart Biosimilar – Anti-BETVIA mAb – Research Grade
Identifiers & database references
Manufacturer SKU
PX-TA2047
UniProt accession
P15494
Storage, stability & shipping
Storage conditions
4°C for short term; -20°C for long term
Shipped at
Blue ice (+4°C)
Compliance & documents
ISO certifications
ISO 9001:2023, ISO 14001: 2023
Datasheet
Open datasheet
Frequently asked questions
Who manufactured this product?

This product is manufactured by ProteoGenix and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

ProteoGenix
£155.00£124.00