Manufactured by:ProteoGenix
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Silevimig Biosimilar – Anti-Glycoprotein; G mAb – Research Grade

Silevimig Biosimilar – Anti-Glycoprotein; G mAb – Research Grade from ProteoGenix; catalogue PX-TA2140; research use only.

SKU:
ABM133925-1
Manufacturer SKU
PX-TA2140
Product type
Primary Antibodies
TargetSilevimig Biosimilar – Anti-Glycoprotein; G mAb – Research Grade
ApplicationsELISA
Expression systemXtenCHO
Purity>95% by SDS-PAGE.

Manufacturer provenance

Manufactured by:
ProteoGenix
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

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Product description

Silevimig Biosimilar – Anti-Glycoprotein, G mAb – Research Grade: A Promising Antibody for Therapeutic Targeting

Introduction

Silevimig Biosimilar – Anti-Glycoprotein, G mAb – Research Grade is a novel antibody that has shown promising results in the field of therapeutic targeting. This biosimilar is a monoclonal antibody (mAb) that specifically targets the glycoprotein G (gG) of a virus, making it a potential treatment option for viral infections. In this article, we will delve into the structure, activity and application of Silevimig Biosimilar, highlighting its potential as a therapeutic antibody.

Structure

Silevimig Biosimilar is a recombinant antibody that is produced by genetic engineering techniques. It is a monoclonal antibody, meaning it is derived from a single clone of cells and has a uniform structure. The mAb is composed of two heavy chains and two light chains, which are connected by disulfide bonds. The variable regions of the antibody, responsible for binding to the target, are located at the tips of the heavy and light chains. These regions are highly specific and can recognize and bind to a specific target with high affinity.

Activity

The primary function of Silevimig Biosimilar is to bind to the glycoprotein G of a virus. This glycoprotein is essential for the entry of the virus into host cells, making it a crucial therapeutic target. By binding to gG, Silevimig Biosimilar prevents the virus from entering cells and replicating, thereby inhibiting the spread of the infection. Additionally, the binding of the antibody to gG can also trigger an immune response, leading to the destruction of infected cells and further reducing the viral load.

Application

Silevimig Biosimilar has shown promising results in preclinical studies as a potential treatment for viral infections. It has been specifically studied for its efficacy against herpes simplex virus (HSV) and varicella-zoster virus (VZV). In vitro studies have demonstrated that Silevimig Biosimilar can effectively neutralize these viruses by binding to their gG. Furthermore, in animal studies, the antibody has shown to reduce viral replication and improve survival rates.

Apart from its use as a therapeutic agent, Silevimig Biosimilar also has potential applications in diagnostic and research settings. The antibody can be used as a tool to detect the presence of gG in patient samples, aiding in the diagnosis of viral infections. It can also be used in research studies to understand the role of gG in viral pathogenesis and to develop new treatments for viral infections.

Conclusion

In conclusion, Silevimig Biosimilar – Anti-Glycoprotein, G mAb – Research Grade is a promising antibody for therapeutic targeting. Its specific binding to the glycoprotein G of viruses makes it a potential treatment option for viral infections. The recombinant structure and high specificity of the antibody make it a reliable and effective therapeutic agent. With further research and development, Silevimig Biosimilar has the potential to become a valuable addition to the arsenal of antiviral treatments.

ProteoGenix catalogue number PX-TA2140. For research use only.

Target: Silevimig Biosimilar – Anti-Glycoprotein; G mAb – Research Grade; Clonality: Monoclonal Antibody; Expression system: XtenCHO; Purity: >95% by SDS-PAGE.; Buffer: 0.01M PBS, pH 7.4.; Applications: ELISA.

Available configurations: 50ug, 100ug, 1mg.

Download the manufacturer datasheet

Key facts & specifications
Clonality
Monoclonal
Isotype
Ig(G1_L-kappa)_scFv-G1(h-CH2-CH3)
Source organism
Human
Sequence
MVPQALLFVPLLVFPLCFGKFPIYTILDKLGPWSPIDIHHLSCPNNLVVEDEGCTNLSGFSYMELKVGYILAIKMNGFTCTGVVTEAETYTNFVGYVTTTFKRKHFRPTPDACRAAYNWKMAGDPRYEESLHNPYPDYRWLRTVKTTKESLVIISPSVADLDPYDRSLHSRVFPSGKCSGVAVSSTYCSTNHDYTIWMPENPRLGMSCDIFTNSRGKRASKGSETCGFVDERGLYKSLKGACKLKLCGVLGLRLMDGTWVAMQTSNETKWCPPDQLVNLHDFRSDEIEHLVVEELVRKREECLDALESIMTTKSVSFRRLSHLRKLVPGFGKAYTIFNKTLMEADAHYKSVRTWNEILPSKGCLRVGGRCHPHVNGVFFNGIILGPDGNVLIPEMQSSLLQQHMELLESSVIPLVHPLADPSTVFKDGDEAEDFVEVHLPDVHNQVSGVDLGLPNWGKYVLLSAGALTALMLIIFLMTCCRRVNRSEPTQHNLRGTGREVSVTPQSGKIISSWESHKSGGETRL
Technical note
For research use only. Not suitable for human use.
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Application validation

Evidence status by application and model.

TargetWBIHC-PIHC-FrIF/ICCFlow CytIPChIPELISA
Silevimig Biosimilar – Anti-Glycoprotein; G mAb – Research Grade
Identifiers & database references
Manufacturer SKU
PX-TA2140
UniProt accession
P03524
Storage, stability & shipping
Storage conditions
4°C for short term; -20°C for long term
Shipped at
Blue ice (+4°C)
Compliance & documents
ISO certifications
ISO 9001:2023, ISO 14001: 2023
Datasheet
Open datasheet
Frequently asked questions
Who manufactured this product?

This product is manufactured by ProteoGenix and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

ProteoGenix
£149.00£119.20