Serrumab Biosimilar – Anti-scorpion venom mAb – Research Grade from ProteoGenix; catalogue PX-TA2027; research use only.
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Serrumab Biosimilar, also known as Anti-scorpion venom mAb – Research Grade, is a monoclonal antibody (mAb) that has been developed as a biosimilar to the therapeutic antibody Serrumab. This biosimilar has been designed to target and neutralize the effects of scorpion venom, providing a potential treatment for scorpion envenomation.
Serrumab Biosimilar is a recombinant humanized IgG1 monoclonal antibody, with a molecular weight of approximately 150 kDa. It is composed of two heavy chains and two light chains, each containing variable and constant regions. The variable regions are responsible for binding to the target, while the constant regions determine the effector functions of the antibody.
Serrumab Biosimilar has been specifically designed to target and bind to a protein in scorpion venom called venom-specific ion channel (VSIC). This protein is responsible for the toxic effects of scorpion venom, including pain, inflammation, and cardiovascular and respiratory complications.
Once bound to VSIC, Serrumab Biosimilar blocks its activity, preventing the release of neurotransmitters and reducing the severity of the symptoms caused by scorpion envenomation. This mechanism of action makes Serrumab Biosimilar a potential therapeutic option for treating scorpion stings.
Serrumab Biosimilar has been developed for research purposes and is not currently approved for clinical use. However, it has shown promising results in preclinical studies and is being further evaluated for its potential as a therapeutic option for scorpion envenomation.
One of the main applications of Serrumab Biosimilar is in the development of antivenoms. Traditional antivenoms are produced by immunizing animals with scorpion venom and collecting the antibodies produced by their immune systems. However, this process is time-consuming, expensive, and can lead to adverse reactions in some individuals. Serrumab Biosimilar, on the other hand, can be produced in large quantities through recombinant technology, making it a more efficient and cost-effective alternative for antivenom production.
Another potential application of Serrumab Biosimilar is in the treatment of scorpion envenomation in humans. Clinical trials are currently underway to evaluate the safety and efficacy of this biosimilar as a therapeutic option for scorpion stings. If successful, Serrumab Biosimilar could provide a much-needed treatment for this potentially life-threatening condition.
In summary, Serrumab Biosimilar is a recombinant humanized monoclonal antibody that has been developed as a biosimilar to the therapeutic antibody Serrumab. It targets and neutralizes the effects of scorpion venom by binding to the venom-specific ion channel, providing a potential treatment option for scorpion envenomation. With further research and clinical trials, Serrumab Biosimilar has the potential to revolutionize the treatment of scorpion stings and improve outcomes for those affected by this condition.
ProteoGenix catalogue number PX-TA2027. For research use only.
Target: Serrumab Biosimilar – Anti-scorpion venom mAb – Research Grade; Clonality: Monoclonal Antibody; Expression system: XtenCHO; Purity: >90% by SDS-PAGE.; Buffer: 0.01M PBS, pH 7.4.; Applications: ELISA, WB.
Available configurations: 50ug, 100ug, 1mg.
Fully tested in-house by ABMIUM, or supported by an advanced validation report from a partner reviewed by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Evidence status by application and model.
| Target | WB | IHC-P | IHC-Fr | IF/ICC | Flow Cyt | IP | ChIP | ELISA |
|---|---|---|---|---|---|---|---|---|
| Serrumab Biosimilar – Anti-scorpion venom mAb – Research Grade |
This product is manufactured by ProteoGenix and sold through ABMIUM without relabelling.
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Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.
