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Sabirnetug Biosimilar – Anti-AICD-57 mAb – Research Grade

Sabirnetug Biosimilar – Anti-AICD-57 mAb – Research Grade from ProteoGenix; catalogue PX-TA1968; research use only.

SKU:
ABM134094-1
Manufacturer SKU
PX-TA1968
Product type
Primary Antibodies
TargetSabirnetug Biosimilar – Anti-AICD-57 mAb – Research Grade
ApplicationsELISA, WB
Expression systemXtenCHO

Manufacturer provenance

Manufactured by:
ProteoGenix
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

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Product description

Introduction to Sabirnetug Biosimilar – Anti-AICD-57 mAb

Sabirnetug Biosimilar – Anti-AICD-57 mAb is a novel monoclonal antibody (mAb) that has been developed as a potential therapeutic agent for the treatment of autoimmune diseases. This biosimilar is a highly specific and potent antibody that targets the AICD-57 protein, which has been identified as a key player in the pathogenesis of various autoimmune disorders. In this article, we will explore the structure, activity, and potential applications of Sabirnetug Biosimilar – Anti-AICD-57 mAb in detail.

Structure of Sabirnetug Biosimilar – Anti-AICD-57 mAb

Sabirnetug Biosimilar – Anti-AICD-57 mAb is a recombinant monoclonal antibody that is produced using advanced biotechnology techniques. It is a fully humanized antibody, meaning that it is derived from human cells and has a high degree of similarity to the natural antibodies found in our body. The antibody consists of two heavy chains and two light chains, which are joined together by disulfide bonds. The heavy chains contain variable and constant regions, while the light chains only have variable regions. The variable regions are responsible for binding to the target protein, AICD-57, while the constant regions are involved in the effector functions of the antibody.

Activity of Sabirnetug Biosimilar – Anti-AICD-57 mAb

The primary mechanism of action of Sabirnetug Biosimilar – Anti-AICD-57 mAb is the specific binding to the AICD-57 protein. AICD-57 is a cell surface protein that is expressed on a variety of immune cells, including T cells and B cells, and is involved in the regulation of immune responses. By binding to AICD-57, Sabirnetug Biosimilar – Anti-AICD-57 mAb blocks its activity and disrupts the signaling pathways that lead to the activation of immune cells. This results in the suppression of inflammatory responses and the restoration of immune homeostasis.

In addition to its inhibitory effect on AICD-57, Sabirnetug Biosimilar – Anti-AICD-57 mAb also has other effector functions, such as antibody-dependent cell-mediated cytotoxicity (ADCC) and complement-dependent cytotoxicity (CDC). These functions allow the antibody to directly target and eliminate cells that express AICD-57, further contributing to its therapeutic effects.

Title: Applications of Sabirnetug Biosimilar – Anti-AICD-57 mAb

Sabirnetug Biosimilar – Anti-AICD-57 mAb has shown promising results in preclinical studies for the treatment of various autoimmune diseases, including rheumatoid arthritis, multiple sclerosis, and systemic lupus erythematosus. These diseases are characterized by dysregulated immune responses, and AICD-57 has been identified as a key factor in their pathogenesis. By targeting AICD-57, Sabirnetug Biosimilar – Anti-AICD-57 mAb has the potential to modulate immune responses and alleviate the symptoms of these diseases.

Furthermore, Sabirnetug Biosimilar – Anti-AICD-57 mAb has also been explored as a potential therapy for solid tumors. AICD-57 has been found to be overexpressed in certain types of cancer, and its inhibition by Sabirnetug Biosimilar – Anti-AICD-57 mAb has shown promising results in preclinical models. This suggests that the antibody may have a broader therapeutic potential beyond autoimmune diseases.

Conclusion

In conclusion, Sabirnetug Biosimilar – Anti-AICD-57 mAb is a novel monoclonal antibody that targets the AICD-57 protein, a key player in the pathogenesis of autoimmune diseases and certain types of cancer. With its highly specific and potent activity, this biosimilar has the potential to be a valuable therapeutic agent in the treatment of these diseases. Further clinical studies are needed to fully evaluate the safety and efficacy of Sabir

ProteoGenix catalogue number PX-TA1968. For research use only.

Target: Sabirnetug Biosimilar – Anti-AICD-57 mAb – Research Grade; Clonality: Monoclonal Antibody; Expression system: XtenCHO; Buffer: 0.01M PBS, pH 7.4; Applications: ELISA, WB.

Available configurations: 50ug, 100ug, 1mg.

Download the manufacturer datasheet

Key facts & specifications
Also known as
anti-AICD-57, A4, Beta-CTF, Protease nexin-II, Gamma-CTF(50), ABPP, S-APP-beta, APP, Abeta40, Abeta42, AID(59), Amyloid intracellular domain 59, AID(57), S-APP-alpha, Gamma-CTF(59), Beta-secretase C-terminal fragment, Amyloid-beta precursor protein, Amyloid precursor protein, Beta-APP42, PreA4, Alzheimer disease amyloid protein, APPI, PN-II, AICD-59, Alpha-secretase C-terminal fragment, Amyloid-beta A4 protein, Amyloid intracellular domain 57, CVAP, Amyloid intracellular domain 50, Beta-APP40, AD1, Cerebral vascular amyloid peptide, AID(50), Alpha-CTF, Gamma-CTF(57), AICD-50
Clonality
Monoclonal
Isotype
IgG2-kappa
Source organism
CAS: 2747959-38-0
Sequence
MLPGLALLLLAAWTARALEVPTDGNAGLLAEPQIAMFCGRLNMHMNVQNGKWDSDPSGTKTCIDTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRCLVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAMSQSLLKTTQEPLARDPVKLPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN
Technical note
For research use only. Not suitable for clinical or therapeutic use.
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Application validation

Evidence status by application and model.

TargetWBIHC-PIHC-FrIF/ICCFlow CytIPChIPELISA
Sabirnetug Biosimilar – Anti-AICD-57 mAb – Research Grade
Identifiers & database references
Manufacturer SKU
PX-TA1968
UniProt accession
P05067
Storage, stability & shipping
Storage conditions
store at -80°C
Shipped at
Blue ice (+4°C)
Compliance & documents
ISO certifications
ISO 9001:2023, ISO 14001: 2023
Datasheet
Open datasheet
Frequently asked questions
Who manufactured this product?

This product is manufactured by ProteoGenix and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

ProteoGenix
£135.00£108.00