Manufactured by:ProteoGenix
Save 20%RUO

Recombinant Mouse FABP4 Protein, N-His

Recombinant Mouse FABP4 Protein, N-His from ProteoGenix; catalogue ARO-P10612; research use only.

SKU:
ABM141053-1
Manufacturer SKU
ARO-P10612
Product type
Recombinant Proteins
Expression systemProkaryotic expression

Manufacturer provenance

Manufactured by:
ProteoGenix
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

Know who made it. See the evidence. Buy through one marketplace.

Product description

Introduction to Recombinant Mouse FABP4 Protein

Recombinant Mouse FABP4 Protein, also known as fatty acid binding protein 4, is a protein that plays a crucial role in lipid metabolism. It is a member of the fatty acid binding protein family, which are small cytoplasmic proteins that bind to fatty acids and other hydrophobic ligands. FABP4 is highly expressed in adipose tissue and is involved in the transport and metabolism of fatty acids. In recent years, recombinant mouse FABP4 protein has gained significant attention in the scientific community due to its potential applications in various fields such as obesity, diabetes, and cardiovascular diseases.

Structure of Recombinant Mouse FABP4 Protein

The recombinant mouse FABP4 protein is a 15 kDa protein composed of 132 amino acids. It has a characteristic beta-barrel structure with ten anti-parallel beta-strands forming a central cavity for ligand binding. FABP4 has a high affinity for long-chain fatty acids and can bind to multiple fatty acids simultaneously. The protein also contains a conserved fatty acid binding pocket, which is critical for its function in fatty acid transport and metabolism.

Activity of Recombinant Mouse FABP4 Protein

The primary function of recombinant mouse FABP4 protein is to facilitate the transport of fatty acids from the cytoplasm to various cellular compartments. It binds to fatty acids and other hydrophobic ligands and transports them to the nucleus, mitochondria, and peroxisomes for energy production and storage. FABP4 also plays a crucial role in regulating lipid metabolism by interacting with various enzymes and signaling pathways.

Moreover, recombinant mouse FABP4 protein has been found to have anti-inflammatory properties. It can regulate the production of inflammatory cytokines and modulate the activity of immune cells, making it a potential therapeutic target for inflammatory diseases.

Application of Recombinant Mouse FABP4 Protein

Recombinant mouse FABP4 protein has a wide range of applications in both basic research and clinical settings. Its role in fatty acid metabolism and inflammation makes it a valuable tool for studying various diseases, including obesity, diabetes, and cardiovascular diseases.

One of the significant applications of recombinant mouse FABP4 protein is in the field of obesity. It has been shown to play a crucial role in the development of obesity-related metabolic disorders. By studying the function of FABP4, researchers can gain a better understanding of the mechanisms underlying obesity and potentially develop new treatments for the condition.

In addition, recombinant mouse FABP4 protein has been identified as a potential biomarker for various diseases. Its expression levels have been found to be altered in conditions such as diabetes, atherosclerosis, and cancer. Measuring FABP4 levels in blood or tissue samples can provide valuable diagnostic and prognostic information for these diseases.

Furthermore, recombinant mouse FABP4 protein has shown promise as a therapeutic target for various diseases. Studies have demonstrated that inhibiting FABP4 activity can improve insulin sensitivity, reduce inflammation, and prevent atherosclerosis. These findings suggest that targeting FABP4 could be a potential strategy for treating obesity, diabetes, and cardiovascular diseases.

Conclusion

Recombinant Mouse FABP4 Protein is a small cytoplasmic protein that plays a critical role in lipid metabolism and inflammation. Its structure and function make it a valuable tool for studying various diseases and developing potential treatments. With ongoing research and advancements in recombinant protein technology, the potential applications of FABP4 are continuously expanding, making it an exciting area of study in the scientific community.

Keywords: recombinant protein, antigen, FABP4, fatty acid binding protein, lipid metabolism, obesity, diabetes, cardiovascular diseases, inflammation

ProteoGenix catalogue number ARO-P10612. For research use only.

Host: Escherichia coli (E.coli); Expression system: Prokaryotic expression; Molecular weight: 16.81 kDa; Fragment: Met1-Ala132; Buffer: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol..

Available configurations: 50ug, 100ug, 1mg.

Download the manufacturer datasheet

Key facts & specifications
Also known as
Adipocyte-type fatty acid-binding protein, Fatty acid-binding protein 4, ALBP, Adipocyte lipid-binding protein, FABP4, A-FABP, Fatty acid-binding protein, adipocyte, AFABP
Host species
E. coli
Source organism
Mouse
Molecular weight
16.81 kDa
Sequence fragment
Met1-Ala132
Sequence
MCDAFVGTWKLVSSENFDDYMKEVGVGFATRKVAGMAKPNMIISVNGDLVTIRSESTFKNTEISFKLGVEFDEITADDRKVKSIITLDGGALVQVQKWDGKSTTIKRKRDGDKLVVECVMKGVTSTRVYERA
Technical note
For research use only.
Identifiers & database references
Manufacturer SKU
ARO-P10612
UniProt accession
P04117
Storage, stability & shipping
Storage conditions
4°C for short term (1 week), -20°C or -80°C for long term (avoid freezing/thawing cycles; addition of 20-40% glycerol improves cryoprotection)
Shipped at
Dry Ice
Compliance & documents
ISO certifications
ISO 9001:2023, ISO 14001: 2023
Datasheet
Open datasheet
Frequently asked questions
Who manufactured this product?

This product is manufactured by ProteoGenix and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

ProteoGenix
£205.00£164.00