Recombinant Human CEP97 Protein, N-His

Recombinant Human CEP97 Protein: A Versatile Tool for Studying Cellular Structure and Function

Introduction
Recombinant proteins have become an indispensable tool in modern molecular biology and biotechnology. These proteins are produced by genetically engineering a host organism, such as bacteria or yeast, to express a specific gene of interest. Recombinant proteins have numerous applications in research, diagnostics, and therapeutics, and their production has revolutionized the study of cellular structure and function. One such protein that has gained significant attention in recent years is Recombinant Human CEP97 Protein.

Structure of Recombinant Human CEP97 Protein
CEP97, also known as centrosomal protein 97, is a large protein consisting of 1,137 amino acids. It is a component of the centrosome, a cellular organelle involved in cell division, and is essential for maintaining the structural integrity of the centrosome. The recombinant form of CEP97 is produced by expressing the CEP97 gene in a suitable host organism, such as Escherichia coli, and purifying the protein using various chromatography techniques.

Activity of Recombinant Human CEP97 Protein
The primary function of CEP97 is to regulate the assembly and organization of the centrosome. It interacts with other centrosomal proteins and plays a crucial role in the formation of the centrosomal matrix, a network of proteins that provides structural support to the centrosome. In addition, CEP97 is involved in the recruitment of proteins to the centrosome and the regulation of centrosome duplication, a process essential for cell division. Recombinant Human CEP97 Protein has been shown to exhibit similar activity to its native form, making it a valuable tool for studying the function of CEP97 in cellular processes.

Applications of Recombinant Human CEP97 Protein
Recombinant Human CEP97 Protein has a wide range of applications in both basic and applied research. Its role in centrosome organization and duplication makes it an essential tool for studying cell division, a process that is dysregulated in various diseases, including cancer. By studying the function of CEP97, researchers can gain insights into the mechanisms of cell division and potentially develop new therapeutic strategies for diseases associated with abnormal cell division.

In addition, Recombinant Human CEP97 Protein has been used in studies to elucidate the role of the centrosome in ciliogenesis, the process of forming cilia, which are hair-like structures on the surface of cells involved in various physiological processes. CEP97 has also been implicated in the regulation of cell migration, a process essential for tissue development and repair. By using recombinant CEP97, researchers can investigate the role of this protein in these and other cellular processes.

Conclusion
Recombinant Human CEP97 Protein is a powerful tool for studying the structure and function of the centrosome. Its recombinant form has been shown to exhibit similar activity to its native counterpart, making it an ideal tool for investigating the role of CEP97 in various cellular processes. With its wide range of applications, Recombinant Human CEP97 Protein has the potential to advance our understanding of cell biology and contribute to the development of new therapeutics for diseases associated with centrosome dysfunction.

ProteoGenix catalogue number ARO-P12432. For research use only.

Host: Escherichia coli (E.coli); Expression system: Prokaryotic expression; Molecular weight: 23.18 kDa; Fragment: Val18-Asn205; Buffer: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol..

Available configurations: 50ug, 100ug, 1mg.

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