Recombinant Human CABYR Protein, N-GST & C-His from ProteoGenix; catalogue ARO-P11355; research use only.
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Recombinant Human CABYR Protein, also known as Calcium-binding tyrosine phosphorylation-regulated protein, is a protein that is encoded by the CABYR gene. This protein is highly conserved among mammalian species and plays a crucial role in various cellular processes such as signal transduction, cell cycle regulation, and protein phosphorylation. In this article, we will discuss the structure, activity, and applications of Recombinant Human CABYR Protein.
Recombinant Human CABYR Protein is a 31 kDa protein consisting of 259 amino acids. It contains a calcium-binding EF-hand domain, a tyrosine phosphorylation site, and a leucine zipper motif. The EF-hand domain is responsible for binding to calcium ions and plays a crucial role in regulating the protein’s activity. The tyrosine phosphorylation site is essential for the protein’s activation, and the leucine zipper motif is involved in protein-protein interactions.
Recombinant Human CABYR Protein is a multifunctional protein that is involved in various cellular processes. It is primarily known for its role in signal transduction, where it acts as a mediator between extracellular signals and intracellular responses. The calcium-binding EF-hand domain of CABYR allows it to sense changes in the calcium concentration and activate downstream signaling pathways. This protein also plays a crucial role in cell cycle regulation by interacting with cyclin-dependent kinases and regulating their activity. Furthermore, Recombinant Human CABYR Protein has been shown to be involved in protein phosphorylation, which is essential for many cellular processes, including cell growth and differentiation.
Recombinant Human CABYR Protein has several potential applications in the field of medicine and biotechnology. One of the primary applications of this protein is its use as an antigen for diagnostic and therapeutic purposes. Antibodies against CABYR have been identified in patients with various types of cancer, including lung, breast, and prostate cancer. Therefore, Recombinant Human CABYR Protein can be used as a biomarker for cancer diagnosis and monitoring.
Moreover, studies have shown that Recombinant Human CABYR Protein is overexpressed in cancer cells, making it a potential target for cancer therapy. Inhibitors of CABYR have been developed, which can potentially inhibit its activity and slow down the growth of cancer cells. This protein has also been shown to be involved in the development of drug resistance in cancer cells, making it a promising target for overcoming drug resistance.
In addition to its role in cancer, Recombinant Human CABYR Protein has also been implicated in other diseases and conditions. For instance, it has been found to be associated with male infertility, where its expression is significantly reduced in infertile men compared to fertile men. This protein has also been linked to neurodegenerative diseases, such as Alzheimer’s and Parkinson’s disease, where it may play a role in the progression of these diseases.
In summary, Recombinant Human CABYR Protein is a multifunctional protein that plays a crucial role in various cellular processes. Its structure, which includes a calcium-binding EF-hand domain, a tyrosine phosphorylation site, and a leucine zipper motif, allows it to perform its diverse functions. This protein has several potential applications in the field of medicine and biotechnology, including its use as an antigen for diagnostic and therapeutic purposes and as a target for cancer therapy. Further research on this protein may uncover more potential applications and shed light on its role in various diseases and conditions.
ProteoGenix catalogue number ARO-P11355. For research use only.
Host: Escherichia coli (E.coli); Expression system: Prokaryotic expression; Molecular weight: 35.16 kDa; Fragment: Gly13-Gly73; Buffer: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol..
Available configurations: 50ug, 100ug, 1mg.
This product is manufactured by ProteoGenix and sold through ABMIUM without relabelling.
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