Manufactured by:ProteoGenix
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Normal Human IgG Isotype Control antibody

Normal Human IgG Isotype Control antibody from ProteoGenix; catalogue PTX17949; research use only.

SKU:
ABM135159-1
Manufacturer SKU
PTX17949
Product type
Primary Antibodies
TargetNormal Human IgG Isotype Control

Manufacturer provenance

Manufactured by:
ProteoGenix
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

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Product description

Introduction

Normal Human IgG Isotype Control antibody is a valuable tool used in various research studies and therapeutic applications. This antibody is a non-specific control for immunoglobulin G (IgG) isotype antibodies and is widely used in immunological research. In this article, we will discuss the structure, activity, and application of Normal Human IgG Isotype Control antibody.

Structure of Normal Human IgG Isotype Control Antibody

Normal Human IgG Isotype Control antibody is a purified, recombinant, monoclonal antibody derived from human IgG1 isotype. It is produced by immunizing mice with human IgG1 and then isolating and purifying the antibody from the mouse serum. The antibody is composed of two heavy chains and two light chains, each containing a constant and variable region. The constant region of the heavy chain is responsible for the antibody’s effector functions, while the variable region is responsible for antigen binding.

Activity of Normal Human IgG Isotype Control Antibody

The main activity of Normal Human IgG Isotype Control antibody is to serve as a non-specific control for IgG isotype antibodies. This means that it does not bind to any specific antigen, but rather serves as a control to compare the activity of other IgG antibodies. It is important to use this control in experiments to ensure that any observed effects are due to the specific antibody being studied and not to non-specific binding or other factors.
Additionally, Normal Human IgG Isotype Control antibody can also be used to block Fc receptors on immune cells, preventing non-specific binding and reducing background noise in experiments. This is especially useful in flow cytometry and immunohistochemistry studies.

Application of Normal Human IgG Isotype Control Antibody

The primary application of Normal Human IgG Isotype Control antibody is in research studies, particularly in immunology and cell biology. It is used as a control in a variety of experiments, including Western blotting, ELISA, flow cytometry, and immunohistochemistry. By using this control, researchers can ensure the specificity and accuracy of their results.
In addition to its use in research, Normal Human IgG Isotype Control antibody also has therapeutic potential. It can be used as a passive immunotherapy agent to treat autoimmune diseases and other disorders. By binding to Fc receptors, this antibody can block the activity of autoantibodies and reduce inflammation and tissue damage. It can also be used in cancer therapy to enhance the activity of other antibodies and immune cells against tumor cells.

Conclusion

Normal Human IgG Isotype Control antibody is a valuable tool in scientific research and therapeutic applications. Its unique structure and activity make it an essential control in experiments involving IgG isotype antibodies. By providing a non-specific control, this antibody ensures the accuracy and specificity of research results. Its potential as a therapeutic agent also makes it a promising candidate for the treatment of various diseases. With its wide range of applications, Normal Human IgG Isotype Control antibody continues to be a crucial component in the advancement of scientific knowledge and medical treatments.

ProteoGenix catalogue number PTX17949. For research use only.

Target: Normal Human IgG Isotype Control; Host: Human; Clonality: Polyclonal Antibody.

Download the manufacturer datasheet

Key facts & specifications
Host species
Human
Clonality
Polyclonal
Isotype
IgG
Source organism
Human
Identifiers & database references
Manufacturer SKU
PTX17949
Storage, stability & shipping
Storage conditions
PBS buffer pH 7.5
Shipped at
Blue ice (+4°C)
Compliance & documents
ISO certifications
ISO 9001:2023, ISO 14001: 2023
Datasheet
Open datasheet
Frequently asked questions
Who manufactured this product?

This product is manufactured by ProteoGenix and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

ProteoGenix
£179.00£143.20