Manufactured by:ProteoGenix
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Imaprelimab Biosimilar – Anti-MCAM mAb – Research Grade

Imaprelimab Biosimilar – Anti-MCAM mAb – Research Grade from ProteoGenix; catalogue PX-TA1512; research use only.

SKU:
ABM134532-1
Manufacturer SKU
PX-TA1512
Product type
Primary Antibodies
TargetImaprelimab Biosimilar – Anti-MCAM mAb – Research Grade
ApplicationsELISA, WB
Expression systemMammalian cells
Purity>85%

Manufacturer provenance

Manufactured by:
ProteoGenix
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

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Product description

Introduction to Imaprelimab Biosimilar – Anti-MCAM mAb – Research Grade

Imaprelimab Biosimilar, also known as Anti-MCAM mAb, is a monoclonal antibody that specifically targets the Melanoma Cell Adhesion Molecule (MCAM). It is a research grade antibody that has been developed as a biosimilar to the original Imaprelimab, which is a therapeutic antibody used in the treatment of various autoimmune diseases. In this article, we will explore the structure, activity, and potential applications of Imaprelimab Biosimilar.

Structure of Imaprelimab Biosimilar – Anti-MCAM mAb

Imaprelimab Biosimilar is a recombinant humanized monoclonal antibody that is produced using advanced biotechnology techniques. It is a fully humanized antibody, meaning that it is derived from human cells, making it less likely to cause an immune response in patients. The antibody is composed of two heavy chains and two light chains, which are connected by disulfide bonds. The heavy chains are responsible for the binding of the antibody to its target, while the light chains provide stability and support.

The specific structure of Imaprelimab Biosimilar allows it to bind to the MCAM protein on the surface of cells. MCAM is a transmembrane glycoprotein that is involved in cell adhesion and migration. By binding to MCAM, Imaprelimab Biosimilar blocks its function, leading to a decrease in inflammation and autoimmune responses.

Activity of Imaprelimab Biosimilar – Anti-MCAM mAb

The primary activity of Imaprelimab Biosimilar is its ability to inhibit the function of MCAM. This function is crucial in the treatment of autoimmune diseases, as it helps to reduce inflammation and prevent further damage to tissues and organs. MCAM is overexpressed in various autoimmune diseases, including psoriasis, rheumatoid arthritis, and multiple sclerosis. By targeting MCAM, Imaprelimab Biosimilar can potentially provide relief to patients suffering from these conditions.

In addition to its anti-MCAM activity, Imaprelimab Biosimilar also has immunomodulatory effects. It can regulate the activity of immune cells, such as T cells and B cells, which play a significant role in autoimmune diseases. By modulating the immune response, Imaprelimab Biosimilar can help to restore balance and reduce the severity of autoimmune reactions.

Title: Applications of Imaprelimab Biosimilar – Anti-MCAM mAb

Imaprelimab Biosimilar has the potential to be used in the treatment of various autoimmune diseases. It is currently being evaluated in clinical trials for the treatment of psoriasis, rheumatoid arthritis, and multiple sclerosis. The biosimilar nature of this antibody allows for a more cost-effective option for patients, making it more accessible for those in need of treatment.

In addition to its potential therapeutic applications, Imaprelimab Biosimilar can also be used in research settings. Its ability to specifically target MCAM makes it a valuable tool for studying the role of this protein in autoimmune diseases. It can also be used to assess the efficacy of other potential treatments that target MCAM, providing valuable insights into the development of new therapies.

Conclusion:

Imaprelimab Biosimilar, also known as Anti-MCAM mAb, is a research grade monoclonal antibody that specifically targets the Melanoma Cell Adhesion Molecule. Its unique structure and activity make it a promising candidate for the treatment of various autoimmune diseases. In addition, its biosimilar nature allows for a more cost-effective option for patients. Further research and clinical trials will determine the full potential of Imaprelimab Biosimilar in the treatment of autoimmune diseases.

ProteoGenix catalogue number PX-TA1512. For research use only.

Target: Imaprelimab Biosimilar – Anti-MCAM mAb – Research Grade; Clonality: Monoclonal Antibody; Expression system: Mammalian cells; Purity: >85%; Buffer: PBS buffer PH7.5; Applications: ELISA, WB.

Available configurations: 50ug, 100ug, 1mg.

Download the manufacturer datasheet

Key facts & specifications
Also known as
Imaprelimab,PRX-003,MCAM,anti-MCAM
Clonality
Monoclonal
Isotype
IgG1-kappa
Source organism
CAS 2014343-04-3
Sequence
MGLPRLVCAFLLAACCCCPRVAGVPGEAEQPAPELVEVEVGSTALLKCGLSQSQGNLSHVDWFSVHKEKRTLIFRVRQGQGQSEPGEYEQRLSLQDRGATLALTQVTPQDERIFLCQGKRPRSQEYRIQLRVYKAPEEPNIQVNPLGIPVNSKEPEEVATCVGRNGYPIPQVIWYKNGRPLKEEKNRVHIQSSQTVESSGLYTLQSILKAQLVKEDKDAQFYCELNYRLPSGNHMKESREVTVPVFYPTEKVWLEVEPVGMLKEGDRVEIRCLADGNPPPHFSISKQNPSTREAEEETTNDNGVLVLEPARKEHSGRYECQGLDLDTMISLLSEPQELLVNYVSDVRVSPAAPERQEGSSLTLTCEAESSQDLEFQWLREETGQVLERGPVLQLHDLKREAGGGYRCVASVPSIPGLNRTQLVNVAIFGPPWMAFKERKVWVKENMVLNLSCEASGHPRPTISWNVNGTASEQDQDPQRVLSTLNVLVTPELLETGVECTASNDLGKNTSILFLELVNLTTLTPDSNTTTGLSTSTASPHTRANSTSTERKLPEPESRGVVIVAVIVCILVLAVLGAVLYFLYKKGKLPCRRSGKQEITLPPSRKSELVVEVKSDKLPEEMGLLQGSSGDKRAPGDQGEKYIDLRH
Technical note
For research use only. Not suitable for clinical or therapeutic use.
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Application validation

Evidence status by application and model.

TargetWBIHC-PIHC-FrIF/ICCFlow CytIPChIPELISA
Imaprelimab Biosimilar – Anti-MCAM mAb – Research Grade
Identifiers & database references
Manufacturer SKU
PX-TA1512
UniProt accession
P43121
Storage, stability & shipping
Storage conditions
store at -80°C
Shipped at
Blue ice (+4°C)
Compliance & documents
ISO certifications
ISO 9001:2023, ISO 14001: 2023
Datasheet
Open datasheet
Frequently asked questions
Who manufactured this product?

This product is manufactured by ProteoGenix and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

ProteoGenix
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