Imaprelimab Biosimilar – Anti-MCAM mAb – Research Grade from ProteoGenix; catalogue PX-TA1512; research use only.
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Imaprelimab Biosimilar, also known as Anti-MCAM mAb, is a monoclonal antibody that specifically targets the Melanoma Cell Adhesion Molecule (MCAM). It is a research grade antibody that has been developed as a biosimilar to the original Imaprelimab, which is a therapeutic antibody used in the treatment of various autoimmune diseases. In this article, we will explore the structure, activity, and potential applications of Imaprelimab Biosimilar.
Imaprelimab Biosimilar is a recombinant humanized monoclonal antibody that is produced using advanced biotechnology techniques. It is a fully humanized antibody, meaning that it is derived from human cells, making it less likely to cause an immune response in patients. The antibody is composed of two heavy chains and two light chains, which are connected by disulfide bonds. The heavy chains are responsible for the binding of the antibody to its target, while the light chains provide stability and support.
The specific structure of Imaprelimab Biosimilar allows it to bind to the MCAM protein on the surface of cells. MCAM is a transmembrane glycoprotein that is involved in cell adhesion and migration. By binding to MCAM, Imaprelimab Biosimilar blocks its function, leading to a decrease in inflammation and autoimmune responses.
The primary activity of Imaprelimab Biosimilar is its ability to inhibit the function of MCAM. This function is crucial in the treatment of autoimmune diseases, as it helps to reduce inflammation and prevent further damage to tissues and organs. MCAM is overexpressed in various autoimmune diseases, including psoriasis, rheumatoid arthritis, and multiple sclerosis. By targeting MCAM, Imaprelimab Biosimilar can potentially provide relief to patients suffering from these conditions.
In addition to its anti-MCAM activity, Imaprelimab Biosimilar also has immunomodulatory effects. It can regulate the activity of immune cells, such as T cells and B cells, which play a significant role in autoimmune diseases. By modulating the immune response, Imaprelimab Biosimilar can help to restore balance and reduce the severity of autoimmune reactions.
Imaprelimab Biosimilar has the potential to be used in the treatment of various autoimmune diseases. It is currently being evaluated in clinical trials for the treatment of psoriasis, rheumatoid arthritis, and multiple sclerosis. The biosimilar nature of this antibody allows for a more cost-effective option for patients, making it more accessible for those in need of treatment.
In addition to its potential therapeutic applications, Imaprelimab Biosimilar can also be used in research settings. Its ability to specifically target MCAM makes it a valuable tool for studying the role of this protein in autoimmune diseases. It can also be used to assess the efficacy of other potential treatments that target MCAM, providing valuable insights into the development of new therapies.
Imaprelimab Biosimilar, also known as Anti-MCAM mAb, is a research grade monoclonal antibody that specifically targets the Melanoma Cell Adhesion Molecule. Its unique structure and activity make it a promising candidate for the treatment of various autoimmune diseases. In addition, its biosimilar nature allows for a more cost-effective option for patients. Further research and clinical trials will determine the full potential of Imaprelimab Biosimilar in the treatment of autoimmune diseases.
ProteoGenix catalogue number PX-TA1512. For research use only.
Target: Imaprelimab Biosimilar – Anti-MCAM mAb – Research Grade; Clonality: Monoclonal Antibody; Expression system: Mammalian cells; Purity: >85%; Buffer: PBS buffer PH7.5; Applications: ELISA, WB.
Available configurations: 50ug, 100ug, 1mg.
Fully tested in-house by ABMIUM, or supported by an advanced validation report from a partner reviewed by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Evidence status by application and model.
| Target | WB | IHC-P | IHC-Fr | IF/ICC | Flow Cyt | IP | ChIP | ELISA |
|---|---|---|---|---|---|---|---|---|
| Imaprelimab Biosimilar – Anti-MCAM mAb – Research Grade |
This product is manufactured by ProteoGenix and sold through ABMIUM without relabelling.
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Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.