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Felmetatug Biosimilar – Anti-VTCN1 – Research Grade

Felmetatug Biosimilar – Anti-VTCN1 – Research Grade from ProteoGenix; catalogue PX-TA2306; research use only.

SKU:
ABM133803-1
Manufacturer SKU
PX-TA2306
Product type
Primary Antibodies
TargetVTCN1
ApplicationsBlocking

Manufacturer provenance

Manufactured by:
ProteoGenix
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

Know who made it. See the evidence. Buy through one marketplace.

Product description

Introduction

Felmetatug Biosimilar – Anti-VTCN1 – Research Grade is a novel antibody that has been developed for the treatment of various diseases. This biosimilar is a highly specific and potent inhibitor of VTCN1, a protein that is involved in immune regulation and has been identified as a therapeutic target for several diseases.

Structure of Felmetatug Biosimilar

Felmetatug Biosimilar is a monoclonal antibody that is produced using recombinant DNA technology. It is a humanized antibody, meaning that it is derived from a non-human source but has been genetically engineered to have a structure that is similar to human antibodies. This allows for better compatibility and reduces the risk of immune reactions in patients.

The antibody has a Y-shaped structure, with two identical heavy chains and two identical light chains. These chains are connected by disulfide bonds and are responsible for the binding of the antibody to its target, VTCN1.

Activity of Felmetatug Biosimilar

Felmetatug Biosimilar has a high affinity for VTCN1, meaning that it binds to the protein with great specificity and strength. This binding prevents VTCN1 from interacting with its receptors on immune cells, thereby inhibiting its activity. VTCN1 is known to play a role in suppressing immune responses, and its overexpression has been linked to various diseases such as cancer, autoimmune disorders, and infectious diseases. By inhibiting VTCN1, Felmetatug Biosimilar helps to restore normal immune function and combat these diseases.

In addition to its inhibitory activity, Felmetatug Biosimilar also has an immunomodulatory effect. It can activate various immune cells, such as T cells and natural killer cells, to enhance their anti-tumor and anti-viral activities. This makes it a promising therapy for diseases that involve dysregulated immune responses.

Application of Felmetatug Biosimilar

Felmetatug Biosimilar is currently being studied as a potential treatment for a variety of diseases, including:

Cancer VTCN1 has been found to be overexpressed in many types of cancer, and its inhibition has shown promising results in preclinical studies. Felmetatug Biosimilar is being investigated as a monotherapy and in combination with other cancer treatments to improve outcomes for cancer patients.

Autoimmune disorders

In autoimmune disorders, the immune system mistakenly attacks healthy cells and tissues. By inhibiting VTCN1, Felmetatug Biosimilar can help regulate the immune response and reduce inflammation in these diseases. It is being studied for the treatment of diseases such as rheumatoid arthritis, multiple sclerosis, and lupus.

Infectious diseases

VTCN1 has been shown to play a role in the immune response to viral and bacterial infections. By inhibiting VTCN1, Felmetatug Biosimilar can enhance the immune response and help fight these infections. It is being investigated as a potential treatment for diseases such as HIV, hepatitis B, and tuberculosis.

Transplant rejection

VTCN1 is involved in the immune response to transplanted organs, and its inhibition has been shown to improve transplant outcomes. Felmetatug Biosimilar is being studied as a potential therapy to prevent transplant rejection and improve the success of organ transplants.

Conclusion

In summary, Felmetatug Biosimilar – Anti-VTCN1 – Research Grade is a novel antibody that has been developed as a potential treatment for various diseases. Its high specificity and potency make it a promising therapy for conditions involving dysregulated immune responses. Further research and clinical trials are needed to fully understand its potential and determine its effectiveness in treating these diseases.

ProteoGenix catalogue number PX-TA2306. For research use only.

Target: VTCN1; Clonality: Monoclonal Antibody; Applications: Block.

Available configurations: 50ug, 100ug, 1mg.

Download the manufacturer datasheet

Key facts & specifications
Also known as
Anti-VTCN1, Anti-B7-H4, Felmetatug vedotin, PF 08046048, PF-08046048, CAS: 159858-33-0
Clonality
Monoclonal
Isotype
IgG
Sequence
MASLGQILFWSIISIIIILAGAIALIIGFGISGRHSITVTTVASAGNIGEDGILSCTFEPDIKLSDIVIQWLKEGVLGLVHEFKEGKDELSEQDEMFRGRTAVFADQVIVGNASLRLKNVQLTDAGTYKCYIITSKGKGNANLEYKTGAFSMPEVNVDYNASSETLRCEAPRWFPQPTVVWASQVDQGANFSEVSNTSFELNSENVTMKVVSVLYNVTINNTYSCMIENDIAKATGDIKVTESEIKRRSHLQLLNSKASLCVSSFFAISWALLPLSPYLMLK
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Application validation

Evidence status by application and model.

TargetWBIHC-PIHC-FrIF/ICCFlow CytIPChIPELISABlock
VTCN1
Identifiers & database references
Manufacturer SKU
PX-TA2306
UniProt accession
Q7Z7D3
Storage, stability & shipping
Storage conditions
4°C for short term (1 week), store at -20°C to -80°C for long term(1 year); Avoid repeated freeze-thaw cycles
Shipped at
Blue ice (+4°C)
Compliance & documents
ISO certifications
ISO 9001:2023, ISO 14001: 2023
Datasheet
Open datasheet
Frequently asked questions
Who manufactured this product?

This product is manufactured by ProteoGenix and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

Research target context

VTCN1V-set domain containing T cell activation inhibitor 1

View target guide

VTCN1 identifies V-set domain containing T cell activation inhibitor 1 in Homo sapiens (Human). This target record connects NCBI Gene 79679, UniProtKB Q7Z7D3 and related ABMIUM catalogue products.

Organism
Multiple species; representative: Homo sapiens (Human)
NCBI Gene
79679
UniProtKB
Q7Z7D3
ProteoGenix
£155.00£124.00