Etentamig Biosimilar – Anti-TNFRSF17;CD3e mAb – Research Grade from ProteoGenix; catalogue PX-TA2191; research use only.
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Title: Introduction to Etentamig Biosimilar – Anti-TNFRSF17;CD3e mAb – Research Grade
Etentamig Biosimilar – Anti-TNFRSF17;CD3e mAb – Research Grade is a therapeutic antibody that has been developed as a biosimilar to the original drug, Etentamig. This biosimilar is designed to target two important proteins, TNFRSF17 and CD3e, which play a crucial role in the immune system. In this article, we will discuss the structure, activity, and application of Etentamig Biosimilar in detail.
Structure of Etentamig Biosimilar
Etentamig Biosimilar is a monoclonal antibody, which means it is produced by a single clone of cells and is therefore highly specific in its action. It is a recombinant protein, meaning that it is produced using genetic engineering techniques. The antibody is composed of two heavy chains and two light chains, which are connected by disulfide bonds. The variable regions of the antibody, responsible for binding to the target proteins, are located at the tips of the two arms of the Y-shaped molecule.
Activity of Etentamig Biosimilar
Etentamig Biosimilar is a dual-targeting antibody, which means it can simultaneously bind to two different proteins, TNFRSF17 and CD3e. TNFRSF17, also known as BCMA, is a receptor found on the surface of B cells, which are a type of immune cells responsible for producing antibodies. CD3e is a protein found on the surface of T cells, which are another type of immune cells responsible for killing infected or abnormal cells. By targeting these two proteins, Etentamig Biosimilar can modulate the activity of both B and T cells, leading to a more coordinated and effective immune response.
Application of Etentamig Biosimilar
Etentamig Biosimilar has a wide range of potential applications in the treatment of various diseases. Its primary use is as a therapeutic antibody for the treatment of autoimmune diseases and cancer. By targeting TNFRSF17 and CD3e, Etentamig Biosimilar can help regulate the activity of the immune system, which is often overactive in autoimmune diseases and underactive in cancer.
In autoimmune diseases such as rheumatoid arthritis and multiple sclerosis, the immune system mistakenly attacks the body’s own tissues. By targeting TNFRSF17 and CD3e, Etentamig Biosimilar can inhibit the activity of B and T cells, which are responsible for this attack. This can help reduce inflammation and prevent further damage to the affected tissues.
In cancer, the immune system is unable to recognize and destroy abnormal cells, allowing them to grow and spread. By targeting TNFRSF17 and CD3e, Etentamig Biosimilar can activate the immune system to recognize and attack cancer cells. This can enhance the body’s natural defense mechanisms and help fight against cancer.
In addition to its therapeutic applications, Etentamig Biosimilar can also be used as a research tool for studying the role of TNFRSF17 and CD3e in various diseases. Its high specificity and dual-targeting ability make it a valuable tool for understanding the complex interactions between different immune cells and their targets.
Conclusion
In summary, Etentamig Biosimilar – Anti-TNFRSF17;CD3e mAb – Research Grade is a promising therapeutic antibody with a unique dual-targeting mechanism. Its structure, activity, and potential applications make it a valuable tool in the treatment of autoimmune diseases and cancer, as well as in research. With further studies and clinical trials, Etentamig Biosimilar has the potential to improve the lives of patients suffering from these diseases.
ProteoGenix catalogue number PX-TA2191. For research use only.
Target: Etentamig Biosimilar – Anti-TNFRSF17;CD3e mAb – Research Grade; Clonality: Monoclonal Antibody; Expression system: XtenCHO; Purity: >95% by SDS-PAGE; Buffer: 0.01M PBS, pH 7.4; Applications: WB.
Available configurations: 50ug, 100ug, 1mg.
Fully tested in-house by ABMIUM, or supported by an advanced validation report from a partner reviewed by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Evidence status by application and model.
| Target | WB | IHC-P | IHC-Fr | IF/ICC | Flow Cyt | IP | ChIP | ELISA |
|---|---|---|---|---|---|---|---|---|
| Etentamig Biosimilar – Anti-TNFRSF17;CD3e mAb – Research Grade |
This product is manufactured by ProteoGenix and sold through ABMIUM without relabelling.
ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.
Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.
