Manufactured by:ProteoGenix
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Ebdarokimab Biosimilar – Anti-IL12B mAb – Research Grade

Ebdarokimab Biosimilar – Anti-IL12B mAb – Research Grade from ProteoGenix; catalogue PX-TA1660; research use only.

SKU:
ABM134388-1
Manufacturer SKU
PX-TA1660
Product type
Primary Antibodies
TargetEbdarokimab Biosimilar – Anti-IL12B mAb – Research Grade
ApplicationsELISA, WB
Expression systemXtenCHO
Purity>85%

Manufacturer provenance

Manufactured by:
ProteoGenix
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

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Product description

Introduction to Ebdarokimab Biosimilar – Anti-IL12B mAb – Research Grade

Ebdarokimab Biosimilar, also known as Anti-IL12B monoclonal antibody (mAb), is a promising therapeutic agent that is currently being developed as a biosimilar to the original Ebdarokimab. This biosimilar is a potent inhibitor of interleukin-12 (IL-12), a cytokine that plays a crucial role in the regulation of immune responses. In this article, we will explore the structure, activity, and potential applications of Ebdarokimab Biosimilar in research.

Structure of Ebdarokimab Biosimilar – Anti-IL12B mAb – Research Grade

Ebdarokimab Biosimilar is a recombinant humanized monoclonal antibody that is composed of two heavy chains and two light chains. The heavy chains are made up of four constant domains (CH1, CH2, CH3, and CH4) and one variable domain (VH), while the light chains contain one constant domain (CL) and one variable domain (VL). The variable domains of both the heavy and light chains are responsible for the binding of Ebdarokimab Biosimilar to its target, IL-12.

Mechanism of Action of Ebdarokimab Biosimilar – Anti-IL12B mAb – Research Grade Ebdarokimab Biosimilar exerts its therapeutic effects by binding to the p40 subunit of IL-12, thereby preventing its interaction with the IL-12 receptor. This results in the inhibition of IL-12 signaling, which is essential for the activation and proliferation of T cells and natural killer cells. By blocking IL-12, Ebdarokimab Biosimilar helps to regulate the immune response and reduce inflammation.

Title: Potential Applications of Ebdarokimab Biosimilar – Anti-IL12B mAb – Research Grade Ebdarokimab Biosimilar has shown promising results in pre-clinical studies and is currently being evaluated for its potential use in various inflammatory and autoimmune diseases. Some of the diseases that could potentially benefit from Ebdarokimab Biosimilar include psoriasis, Crohn’s disease, rheumatoid arthritis, and multiple sclerosis. Additionally, this biosimilar could also be used in the treatment of certain types of cancer, as IL-12 has been shown to have anti-tumor effects.

Advantages of Ebdarokimab Biosimilar – Anti-IL12B mAb – Research Grade

One of the main advantages of Ebdarokimab Biosimilar is its similarity to the original Ebdarokimab, which has been extensively studied and has a proven safety and efficacy profile. This biosimilar also offers a lower cost alternative to the original drug, making it more accessible to patients. Furthermore, Ebdarokimab Biosimilar is produced using recombinant DNA technology, ensuring consistency and quality in every batch.

Title: Research Grade Ebdarokimab Biosimilar – Anti-IL12B mAb for Scientific Studies Ebdarokimab Biosimilar is currently being developed as a research-grade product, making it an ideal tool for scientific studies. Its high specificity and potency make it a valuable tool for investigating the role of IL-12 in various disease models. Additionally, the availability of a research-grade biosimilar allows for more cost-effective and efficient research, as compared to using the original drug.

Conclusion

In conclusion, Ebdarokimab Biosimilar – Anti-IL12B mAb – Research Grade is a promising therapeutic agent that has the potential to be used in the treatment of various inflammatory and autoimmune diseases. Its structure, mechanism of action, and potential applications make it a valuable tool for scientific research. With further development and clinical trials, Ebdarokimab Biosimilar could potentially offer a more affordable and accessible treatment option for patients in need.

ProteoGenix catalogue number PX-TA1660. For research use only.

Target: Ebdarokimab Biosimilar – Anti-IL12B mAb – Research Grade; Clonality: Monoclonal Antibody; Expression system: XtenCHO; Purity: >85%; Buffer: PBS buffer PH7.5; Applications: ELISA, WB.

Available configurations: 50ug, 100ug, 1mg.

Download the manufacturer datasheet

Key facts & specifications
Also known as
Ebdarokimab,AK-101, EBDAROKIMAB, EBDAROKIMAB, IMMUNOGLOBULIN G1, ANTI-(HUMAN INTERLEUKIN 12 SUBUNIT .BETA.) (HUMAN MONOCLONAL AK101 .GAMMA.1-CHAIN), DISULFIDE WITH HUMAN MONOCLONAL AK101 .KAPPA.-CHAIN, DIMER,IL12B,anti-IL12B
Clonality
Monoclonal
Isotype
IgG1,Kappa
Source organism
CAS 2393651-11-9
Sequence
MCHQQLVISWFSLVFLASPLVAIWELKKDVYVVELDWYPDAPGEMVVLTCDTPEEDGITWTLDQSSEVLGSGKTLTIQVKEFGDAGQYTCHKGGEVLSHSLLLLHKKEDGIWSTDILKDQKEPKNKTFLRCEAKNYSGRFTCWWLTTISTDLTFSVKSSRGSSDPQGVTCGAATLSAERVRGDNKEYEYSVECQEDSACPAAEESLPIEVMVDAVHKLKYENYTSSFFIRDIIKPDPPKNLQLKPLKNSRQVEVSWEYPDTWSTPHSYFSLTFCVQVQGKSKREKKDRVFTDKTSATVICRKNASISVRAQDRYYSSSWSEWASVPCS
Technical note
For research use only. Not suitable for clinical or therapeutic use.
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Application validation

Evidence status by application and model.

TargetWBIHC-PIHC-FrIF/ICCFlow CytIPChIPELISA
Ebdarokimab Biosimilar – Anti-IL12B mAb – Research Grade
Identifiers & database references
Manufacturer SKU
PX-TA1660
UniProt accession
P29460
Storage, stability & shipping
Storage conditions
store at -80°C
Shipped at
Blue ice (+4°C)
Compliance & documents
ISO certifications
ISO 9001:2023, ISO 14001: 2023
Datasheet
Open datasheet
Frequently asked questions
Who manufactured this product?

This product is manufactured by ProteoGenix and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

ProteoGenix
£139.00£111.20