Dibotatug Biosimilar – Anti-Killer cell lectin-like receptor subfamily D member 1 mAb – Research Grade from ProteoGenix; catalogue PX-TA2186; research
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Dibotatug Biosimilar – Anti-Killer cell lectin-like receptor subfamily D member 1 mAb – Research Grade is a therapeutic antibody that has been developed as a biosimilar to a well-known therapeutic antibody targeting the Killer cell lectin-like receptor subfamily D member 1 (KLRD1). This biosimilar has been designed to mimic the structure and function of the original therapeutic antibody, providing a more affordable and accessible option for patients in need of this treatment.
Dibotatug Biosimilar is a monoclonal antibody (mAb) that is produced by cloning a single type of immune cell, known as a B-cell, in the laboratory. This process results in a highly specific antibody that targets a specific protein on the surface of cells. In the case of Dibotatug Biosimilar, the target protein is KLRD1, which is found on the surface of certain immune cells.
The structure of Dibotatug Biosimilar is similar to that of the original therapeutic antibody, with a variable region that binds to the target protein and a constant region that mediates the antibody’s effector functions. This structure is crucial for the antibody’s ability to recognize and bind to the target protein, leading to its therapeutic effects.
Dibotatug Biosimilar works by binding to KLRD1 on the surface of immune cells, specifically natural killer (NK) cells and T cells. This binding blocks the interaction between KLRD1 and its ligand, resulting in the inhibition of immune cell activation and proliferation. This mechanism of action is similar to that of the original therapeutic antibody, making Dibotatug Biosimilar an effective alternative for treating conditions where KLRD1 plays a role.
The activity of Dibotatug Biosimilar has been extensively studied in preclinical and clinical trials, demonstrating its ability to effectively block KLRD1 and its therapeutic potential in various diseases. This biosimilar has shown promising results in treating autoimmune disorders, inflammatory diseases, and certain types of cancer.
Dibotatug Biosimilar is primarily used as a therapeutic antibody for the treatment of diseases where KLRD1 is a therapeutic target. This includes conditions such as rheumatoid arthritis, psoriasis, and various types of cancer.
In addition to its therapeutic applications, Dibotatug Biosimilar is also used in research settings to study the role of KLRD1 in various diseases and to develop new treatment strategies. Its availability as a research grade biosimilar allows for more affordable and accessible access to this important therapeutic target, leading to further advancements in the field of immunology.
In summary, Dibotatug Biosimilar – Anti-Killer cell lectin-like receptor subfamily D member 1 mAb – Research Grade is a highly specific and effective therapeutic antibody that targets KLRD1. Its structure, activity, and application make it a valuable tool for both therapeutic and research purposes. As a biosimilar, it provides a more affordable and accessible option for patients in need of this treatment, ultimately improving patient outcomes and advancing the field of immunology.
ProteoGenix catalogue number PX-TA2186. For research use only.
Target: Dibotatug Biosimilar – Anti-Killer cell lectin-like receptor subfamily D member 1 mAb – Research Grade; Clonality: Monoclonal Antibody; Expression system: XtenCHO; Purity: >95% by SDS-PAGE; Buffer: 0.01M PBS, pH 7.4; Applications: ELISA.
Available configurations: 50ug, 100ug, 1mg.
Fully tested in-house by ABMIUM, or supported by an advanced validation report from a partner reviewed by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Evidence status by application and model.
| Target | WB | IHC-P | IHC-Fr | IF/ICC | Flow Cyt | IP | ChIP | ELISA |
|---|---|---|---|---|---|---|---|---|
| Dibotatug Biosimilar – Anti-Killer cell lectin-like receptor subfamily D member 1 mAb – Research Grade |
This product is manufactured by ProteoGenix and sold through ABMIUM without relabelling.
ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.
Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.
