Bexatamig Biosimilar – Anti-CD123;CD335 mAb – Research Grade from ProteoGenix; catalogue PX-TA2177; research use only.
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Introduction
Bexatamig Biosimilar – Anti-CD123;CD335 mAb – Research Grade is a therapeutic antibody that targets two important receptors, CD123 and CD335, on the surface of cancer cells. This biosimilar is designed to mimic the structure and function of the original therapeutic antibody, Bexatamig, and is used in cancer research to understand the role of CD123 and CD335 in cancer progression and to develop new therapies.
Structure
Bexatamig Biosimilar is a monoclonal antibody, which means it is produced from a single type of immune cell. It is composed of two heavy chains and two light chains, connected by disulfide bonds. The heavy chains contain the antigen-binding region, which recognizes and binds to CD123 and CD335 on the surface of cancer cells. The light chains are responsible for stabilizing the structure of the antibody.
Activity
Bexatamig Biosimilar works by binding to CD123 and CD335 receptors on the surface of cancer cells. CD123 is a type of interleukin-3 receptor, which is found on the surface of leukemic stem cells and is involved in cell proliferation and survival. CD335, also known as natural killer cell receptor, is found on the surface of natural killer cells, a type of immune cell that plays a crucial role in fighting cancer.
By binding to these receptors, Bexatamig Biosimilar blocks the signaling pathways that promote cancer cell growth and survival. It also activates natural killer cells to attack and kill cancer cells, leading to tumor regression. This mechanism of action makes Bexatamig Biosimilar a promising therapeutic antibody for the treatment of various types of cancer.
Application
Bexatamig Biosimilar – Anti-CD123;CD335 mAb – Research Grade has multiple applications in cancer research. Firstly, it can be used to study the role of CD123 and CD335 in cancer progression. By blocking these receptors, researchers can observe the effects on cancer cell growth and survival, providing valuable insights into the underlying mechanisms of cancer.
Secondly, Bexatamig Biosimilar can be used to develop new therapies targeting CD123 and CD335. By understanding the structure and activity of this biosimilar, researchers can design more effective and specific therapeutic antibodies for the treatment of cancer.
Furthermore, Bexatamig Biosimilar can also be used in pre-clinical studies to assess its safety and efficacy before being tested in clinical trials. This is an important step in the drug development process to ensure that the biosimilar is safe and effective for use in humans.
Conclusion
In summary, Bexatamig Biosimilar – Anti-CD123;CD335 mAb – Research Grade is a therapeutic antibody that targets CD123 and CD335 receptors on the surface of cancer cells. Its structure and activity make it a promising candidate for cancer research and the development of new therapies. By understanding the role of CD123 and CD335 in cancer, researchers can use this biosimilar to advance our knowledge and improve treatment options for cancer patients.
ProteoGenix catalogue number PX-TA2177. For research use only.
Target: Bexatamig Biosimilar – Anti-CD123;CD335 mAb – Research Grade; Clonality: Monoclonal Antibody; Expression system: XtenCHO; Purity: >95% by SDS-PAGE; Buffer: 0.01M PBS, pH 7.4; Applications: WB.
Available configurations: 50ug, 100ug, 1mg.
Fully tested in-house by ABMIUM, or supported by an advanced validation report from a partner reviewed by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Evidence status by application and model.
| Target | WB | IHC-P | IHC-Fr | IF/ICC | Flow Cyt | IP | ChIP | ELISA |
|---|---|---|---|---|---|---|---|---|
| Bexatamig Biosimilar – Anti-CD123;CD335 mAb – Research Grade |
This product is manufactured by ProteoGenix and sold through ABMIUM without relabelling.
ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.
Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.
