Baminercept Alfa Biosimilar – Anti-LT-alpha,beta, LIGHT fusion protein – Research Grade from ProteoGenix; catalogue PX-TA2003; research use only.
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Baminercept Alfa Biosimilar, also known as Anti-LT-alpha,beta, LIGHT fusion protein, is a novel therapeutic agent that has shown promising results in the treatment of various inflammatory diseases. This biosimilar is a fusion protein that combines the properties of two important cytokines, LT-alpha and LIGHT, to target and modulate the immune response. In this scientific web content, we will delve into the structure, activity, and potential applications of Baminercept Alfa Biosimilar as a research grade antibody.
Baminercept Alfa Biosimilar is a recombinant fusion protein that consists of two main components, LT-alpha and LIGHT. LT-alpha is a cytokine that belongs to the tumor necrosis factor (TNF) superfamily and is involved in the regulation of immune response and inflammation. LIGHT, on the other hand, is a member of the TNF superfamily that plays a crucial role in the activation of immune cells and the production of pro-inflammatory cytokines.
The fusion protein is created by linking the extracellular domain of LT-alpha to the extracellular domain of LIGHT, resulting in a single molecule with dual activity. This unique structure allows Baminercept Alfa Biosimilar to target and modulate the immune response through two different pathways simultaneously.
Baminercept Alfa Biosimilar acts as a competitive inhibitor of LT-alpha and LIGHT, preventing these cytokines from binding to their respective receptors. By blocking the activity of these cytokines, Baminercept Alfa Biosimilar can effectively modulate the immune response and reduce inflammation.
LT-alpha and LIGHT are known to play a crucial role in the development of autoimmune diseases, such as rheumatoid arthritis and inflammatory bowel disease. By inhibiting their activity, Baminercept Alfa Biosimilar has the potential to treat these conditions and provide relief to patients.
Additionally, Baminercept Alfa Biosimilar has been shown to have a synergistic effect with other TNF inhibitors, such as infliximab and etanercept. This means that it can enhance the therapeutic effect of these drugs and potentially reduce the dosage and frequency of administration.
As a research grade antibody, Baminercept Alfa Biosimilar has a wide range of potential applications in the field of immunology. It can be used to study the role of LT-alpha and LIGHT in various inflammatory diseases and to develop new therapeutic strategies.
In addition, Baminercept Alfa Biosimilar can also be used as a tool to investigate the mechanism of action of other TNF inhibitors and to explore potential combinations for more effective treatment.
Moreover, Baminercept Alfa Biosimilar has the potential to be developed as a therapeutic agent for various inflammatory diseases. Clinical trials have shown promising results in the treatment of rheumatoid arthritis, psoriasis, and psoriatic arthritis. Further studies are needed to fully understand the potential of this biosimilar in treating these conditions.
In summary, Baminercept Alfa Biosimilar is a novel fusion protein that combines the properties of LT-alpha and LIGHT to target and modulate the immune response. Its unique structure and activity make it a promising therapeutic agent for various inflammatory diseases. As a research grade antibody, it has the potential to advance our understanding of the role of LT-alpha and LIGHT in the immune system and to develop new treatments for autoimmune diseases. Further research and clinical trials are needed to fully explore the potential of Baminercept Alfa Biosimilar in the field of immunology.
ProteoGenix catalogue number PX-TA2003. For research use only.
Target: Baminercept Alfa Biosimilar – Anti-LT-alpha,beta, LIGHT fusion protein – Research Grade; Expression system: XtenCHO; Purity: >90% by SDS-PAGE.; Buffer: 0.01M PBS, pH 7.4.; Applications: ELISA, WB.
Available configurations: 50ug, 100ug, 1mg.
Fully tested in-house by ABMIUM, or supported by an advanced validation report from a partner reviewed by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Evidence status by application and model.
| Target | WB | IHC-P | IHC-Fr | IF/ICC | Flow Cyt | IP | ChIP | ELISA |
|---|---|---|---|---|---|---|---|---|
| Baminercept Alfa Biosimilar – Anti-LT-alpha,beta, LIGHT fusion protein – Research Grade |
This product is manufactured by ProteoGenix and sold through ABMIUM without relabelling.
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Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.
