Manufactured by:ProteoGenix
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Anti-Human IA-2/PTPRN Antibody (76F)

Anti-Human IA-2/PTPRN Antibody (76F) from ProteoGenix; catalogue ARO-A22823; research use only.

SKU:
ABM121169-1
Manufacturer SKU
ARO-A22823
Product type
Primary Antibodies
TargetReceptor-type tyrosine-protein phosphatase-like N, R-PTP-N, Islet cell antigen 512, ICA 512, Islet cell autoantigen 3, PTP IA-2, ICA512-N-terminal fragment, ICA512-NTF, ICA512-transmembrane fragment, ICA512-TMF, ICA512-cleaved cytosolic fragment, ICA512-CCF, PTPRN, ICA3, ICA512
ApplicationsIHC, IP
Species / reactivityHuman

Manufacturer provenance

Manufactured by:
ProteoGenix
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

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Product description

Anti-Human IA-2/PTPRN Antibody (76F)

Biological Function

The Anti-Human IA-2/PTPRN Antibody (76F) is a highly specific and sensitive antibody that targets the IA-2/PTPRN protein. This protein is a member of the protein tyrosine phosphatase family and is primarily expressed in pancreatic islet cells. The main function of IA-2/PTPRN is to regulate insulin secretion and maintain glucose homeostasis.

Main Applications

This antibody is a valuable tool for researchers studying the pathogenesis of type 1 diabetes. It can also be used for diagnostic purposes in patients with type 1 diabetes, as IA-2/PTPRN is a major autoantigen in this disease. Additionally, this antibody has shown potential for use in the development of therapeutic treatments for type 1 diabetes.

Experimental Use Cases

The Anti-Human IA-2/PTPRN Antibody (76F) has been used in various experimental studies to investigate the role of IA-2/PTPRN in type 1 diabetes. In one study, it was used to detect the presence of IA-2/PTPRN autoantibodies in patients with type 1 diabetes. Another study utilized this antibody to investigate the effects of IA-2/PTPRN on insulin secretion in pancreatic islet cells.

In addition to its role in diabetes research, this antibody has also been used in studies related to other autoimmune diseases, such as rheumatoid arthritis and multiple sclerosis. Its high specificity and sensitivity make it a valuable tool for identifying IA-2/PTPRN as a potential biomarker for these diseases.

The Anti-Human IA-2/PTPRN Antibody (76F) is a powerful tool for researchers studying type 1 diabetes and other autoimmune diseases. Its specificity and sensitivity make it ideal for detecting IA-2/PTPRN and its potential role in disease pathogenesis. This antibody can also be used for diagnostic purposes and has shown potential for use in the development of therapeutic treatments.

Structure

To summarize, the Anti-Human IA-2/PTPRN Antibody (76F) is a highly specific and sensitive antibody that targets the IA-2/PTPRN protein. Its main applications include research on type 1 diabetes and other autoimmune diseases, as well as diagnostic and therapeutic purposes. This antibody has been used in various experimental studies and has shown promising results in identifying IA-2/PTPRN as a potential biomarker and therapeutic target. Choose the Anti-Human IA-2/PTPRN Antibody (76F) for reliable and accurate results in your research and diagnostic needs.

ProteoGenix catalogue number ARO-A22823. For research use only.

Target: Receptor-type tyrosine-protein phosphatase-like N, R-PTP-N, Islet cell antigen 512, ICA 512, Islet cell autoantigen 3, PTP IA-2, ICA512-N-terminal fragment, ICA512-NTF, ICA512-transmembrane fragment, ICA512-TMF, ICA512-cleaved cytosolic fragment, ICA512-CCF, PTPRN, ICA3, ICA512; Clonality: Monoclonal Antibody; Reactivity: Human; Applications: IHC, IP.

Available configurations: 50ug, 100ug, 1mg.

Download the manufacturer datasheet

Key facts & specifications
Also known as
Anti-Receptor-type tyrosine-protein phosphatase-like N, R-PTP-N, Islet cell antigen 512, ICA 512, Islet cell autoantigen 3, PTP IA-2, ICA512-N-terminal fragment, ICA512-NTF, ICA512-transmembrane fragment, ICA512-TMF, ICA512-cleaved cytosolic fragment, ICA512-CCF, PTPRN, ICA3, ICA512
Clonality
Monoclonal
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Application validation

Evidence status by application and model.

SpeciesWBIHC-PIHC-FrIF/ICCFlow CytIPChIPELISAIHC
Human
Identifiers & database references
Manufacturer SKU
ARO-A22823
Storage, stability & shipping
Storage conditions
4°C for short term (1 week), store at -20°C to -80°C for long term(1 year); Avoid repeated freeze-thaw cycles
Shipped at
Blue ice (+4°C)
Compliance & documents
ISO certifications
ISO 9001:2023, ISO 14001: 2023
Datasheet
Open datasheet
Frequently asked questions
Who manufactured this product?

This product is manufactured by ProteoGenix and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

ProteoGenix
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